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The choroid in pregnancy
During pregnancy there can be different types of ocular changes including a decrease in corneal sensitivity, increase in central corneal thickness and curvature, decrease in intraocular pressure, central serous chorioretinopathy and ocular blood flow. Advances in ophthalmic imaging devices has...
Blinking and driving
Spontaneous blinking is dependent on cognitive processes and is regulated by a central pacemaker that is highly sensitive to the attention demands and cognitive workload of the visual task in hand. There is evidence of a variability in the frequency...
A review of chromosome 9p21 POAG susceptibility locus
Primary open angle glaucoma (POAG) is a genetically complex disease and the overall phenotype is influenced by multiple traits including intraocular pressure (IOP), central corneal thickness and structural features of the optic nerve head. Therefore, genes affecting any of these...The 103rd Oxford Ophthalmological Congress
By Rachel Pilling, Consultant Ophthalmologist, Bradford Teaching Hospital. As the 103rd Oxford Ophthalmological Congress draws to a close, we reflect back on an enlightening and enriching four days. One of the defining features of Oxford Congress is single stream programme...
New mouse model of diabetes mellitus
Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...
Association between serum triglycerides and pan retinal photocoagulation in type 1 diabetes
This retrospective cohort study aimed to examine whether dyslipidaemia is a risk factor for progressing to proliferative diabetic retinopathy (PDR) and consequently requiring pan retinal photocoagulation (PRP) treatment in type 1 diabetics. In previous studies including the ETDRS study an...
Is intracranial pressure affected by the valsalva manoeuvres and exercise?
Idiopathic intracranial hypertension (IIH) is characterised by elevated intracranial pressure (ICP), which leads to optic nerve head swelling and a risk of visual loss. The impact of straining and exercise on ICP regulation is poorly understood yet clinically relevant to...
