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Risk of developing pseudotumor cerebri in women using a levonorgesteral intrauterine device
Pseudotumor cerebri (PCT) is a disorder causing increased intracranial pressure without a mass lesion, usually seen in obese women of childbearing age. Idiopathic intracranial hypertension is an idiopathic form of the disorder, but several medications have been associated with the...
Outcomes of cataract surgery in eyes with weak zonules
Pseudoexfoliation (PEX) and zonular weakness have long been known to increase the risk of complication of cataract surgery. This retrospective study looks at the results of phacoemulsion and intraocular implantation in 295 eyes with pseudoexfoliation and zonular weakness, with a...
Conjunctivochalasis and aqueous tear deficiency – which one causes symptoms?
This review sought to determine whether conjunctivochalasis (CCh) obliterates the fornix tear reservoir and thus mimics aqueous tear deficiency (ATD). Patients were divided into two groups, with aqueous tear deficiency (CCh +ATD) or without (CCh –ATD), based on results of...
Differential diagnosis in cases of suspected neuroretinitis
Neuroretinitis is a form of optic neuropathy typically characterised by acute unilateral visual loss with optic disc oedema and macular exudates arranged in a star figure around the fovea (complete or partial star). The purpose of this study was to...Eye scans detect signs of Parkinson’s disease up to seven years before diagnosis
A team led by Siegfried Wagner and Pearse Keane of Moorfields Eye Hospital and UCL Institute of Ophthalmology (and spanning UCL institutions) has identified markers that indicate the presence of Parkinson’s disease in patients on average seven years before clinical presentation.
Positive diagnosis of acute posterior ischaemic optic nerve neuropathy
Posterior ischaemic optic neuropathy is a rare cause of visual loss believed to be due to infarction in the territory of the pial branches of the ophthalmic artery. There is an absence of clinical signs which means the diagnosis is...
Review of paediatric infectious endophthalmitis
This paper presents a review on paediatric infectious endophthalmitis and considers aetiology, prognosis and management. Classification included exogenous and endogenous. Diagnosis was based on presenting history, signs and symptoms, cultures and imaging. Exogenous cases included postoperative endophthalmitis (strabismus surgery, glaucoma...
A mouse model for uveal melanoma
Uveal melanoma (UM) is the most common malignant tumour arising within the eye and is a severe threat for both sight and life, due to a high risk of metastasis. There are no animal models of UM, but the Tg(Grm1)...
Long-term outcomes for hereditary retinoblastoma
Earlier diagnosis and more rigorous treatment regimens have contributed to better outcomes for patients with retinoblastoma. This study looked at 24 patients with hereditary bilateral retinoblastoma treated with systemic chemotherapy during a ten year period (2001-2011). The medical notes were...
Identification and diagnosis of thalamic haemorrhage
This paper presents a case of thalamic haemorrhage and discusses clinical findings, providing valuable insight into signs clinicians need to look for. The case presented is of a 76-year-old female who developed left hemiplegia and hemi anaesthesia. Ocular motility testing...
Analysis and outcome of explanted hydroxyapatite orbital implants
This is a retrospective case series over 11 years of 25 patients with exposed synthetic hydroxyapatite orbital implants who underwent explantation and simultaneous replacement with a dermis fat graft. All patients had signs of infection and had been treated with...
