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Corneal molecular and cellular biology for refractive surgeon
This is an interesting literature review that looks into the recent advances concerning the corneal molecular and cellular processes that are involved in the wound healing response after excimer laser surface ablation and LASIK surgery. It talks about the complex...
MicroRNAs in cataract
In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...
Maintenance therapy for CMV endotheliitis
Cytomegalovirus (CMV) has been associated with corneal endotheliitis, leading to endothelial cell loss and corneal decompensation. CMV corneal endotheliitis recurrence can affect between 5-60% of eyes after cessation of anti-CMV therapy. Each recurrence of endotheliitis has a detrimental effect on...
Progression in the Early Manifest Glaucoma Trial
The Early Manifest Glaucoma Trial (EMGT) had previously demonstrated without doubt that intraocular pressure reduction decreased the risk of progression in patients with early glaucoma. In this analysis of 306 eyes over eight years from the EMGT, perimetric and optic...
Comparison of treatment for hemianopia following stroke
The authors report the screening process and recruitment figures for a randomised controlled trial comparing interventions for post stroke homonymous hemianopia. Interventions included Fresnel prisms, visual search training and standard care (information only). Primary outcome measure was the change in...
Characteristics and incidence of sixth nerve palsy in children with intracranial hypertension
The authors report the incidence and characteristics of sixth cranial nerve palsy in paediatric patients with intracranial hypertension. A retrospective review of records was performed in central Ohio over a three year period and nine children were found to have...
Use of RAPDx device with optic nerve disease
The authors have previously reported on use of the RAPDx device for evaluating relative afferent pupillary defects (RAPD). RAPDx objectively determines the magnitude of RAPD by presenting light stimuli alternately to pairs of eyes with laterality. The parameters of amplitude...
A population based follow-up study on pseudoexfoliation and cataract surgery
n association between pseudoexfoliation (PEX) and cataracts has been shown in many previous studies. Recently, the Australian Blue Mountains Eye Study, using the Wisconsin Cataract Typing and Grading System, observed an increased prevalence of nuclear cataract in eyes with PEX....
Familial Mediterranean Fever and keratoconus
This retrospective case control study was conducted in the Genetic Diagnostic Centre in Turkey. It examined the prevalence of keratoconus in two groups; patients with Familial Mediterranean Fever (FMF) and age matched controls free of FMF, who were tested for...
Myopia in Han Chinese
The authors present a case-control study of 361 patients with high myopia (mean spherical equivalent of -6.0DS or lower, and axial length greater than or equal to 26mm) and 749 healthy controls (mean spherical equivalent -1.0 to +1.0DS). They tested...
Comparison of central laminar thickness in optic neuropathy and normal eyes
The study compares central laminar thickness (LT) among patients with glaucomatous optic neuropathy (GON), patients with non-GON and normal subjects. The non-GON group comprised eyes with demyelinating optic neuropathy (ON), anterior ischaemic ON, compressive ON, Leber hereditary ON and traumatic...
