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A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention
To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....The University of Edinburgh - Supporting Future Leaders in Ophthalmology
The University of Edinburgh announce plan to award twelve scholarships this summer for successful international applicants to their Master of Surgery (ChM) in Clinical Ophthalmology programme. Deadline for application closes 15th June.Breakthroughs in the genetics of angle-closure glaucoma
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...Hydroxychloroquine toxicity
Being the subject of litigation is stressful and upsetting. Having to look back over your previous decisions and justify the care you delivered in good faith can be difficult. Sadly, we all live with the Sword of Damocles above us...
Congenital aniridia with or without retinal detachment
The authors present the clinical and molecular genetic evaluations performed on a large Iranian pedigree with 26 aniridia affected patients in four generations and some with retinal detachment. Members of the family affected with aniridia were invited to participate after...Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...Sustainable prevention of blindness from diabetic retinopathy through prevention and control of diabetes mellitus – LINK partnership experience in Dominica
The Caribbean Diabetic Retinopathy Project (DR Caribbean) is a five-year project that aims to reduce blindness due to diabetic retinopathy (DR) across four Commonwealth countries: Belize, Dominica, Jamaica and St Lucia. The VISION 2020 LINKS Programme at the London School...Developing a training model to strengthen diabetic retinopathy screening through a VISION 2020 LINK in India
I. Development of LINK Partnership A VISION 2020 LINK India was established by signing a Memorandum of Understanding (MoU) in 2018 between the Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India, Frimley Health NHS Foundation Trust and...
A standardised strategy for uveitis etiological diagnosis
This was a prospective, non-inferiority, multicentre randomised control trial, which aimed to assess the effectiveness of a standardised approach in the etiological diagnosis of uveitis versus an open strategy, where clinicians could perform any test. The authors developed their standardised...Papilloedema: an update
Some readers may have seen a recent report in the national newspapers of the case of a teenage girl with persistent severe headache associated with a fatal brain tumour having been undiagnosed despite many consultations with her medical advisers. It...Forward-tilt technique for intraocular pressure measurement in upgaze
The authors suggest a technique to improve the accuracy of measuring IOP in upgaze using Goldmann applanation tonometry. Graves’ ophthalmopathy, also known as thyroid eye disease, is an autoimmune inflammatory condition affecting the orbit and periorbital tissues [1]. It was...
