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FAZ measurement on OCTA

This paper aimed to test the AngioVue OCTAs reproducibility and interoperator concordance in evaluating the size of the foveal avascular zone (FAZ). The authors also investigated how the FAZs representation on the OCTA varied after metabolic activity. The right eye...

Vision loss during Eylea treatment for AMD

This report investigated patients who lost more than two lines of vision despite periodic injections of aflibercept and explored the factors associated with vision loss. One hundred and ninety-six eyes were included in this study over a two year period....

What about the children? Cornea cross-linking for children with keratoconus

Keratoconus can behave more aggressively in paediatric than in adult patients. Collagen cross-linking has been shown to slow the progression of keratoconus in adults. This systematic review determined the effectiveness of corneal collagen cross-linking (CXL) in children. For this study,...

Retinotopic fMRI reveals visual dysfunction and functional reorganisation in the visual cortex of glaucoma patients

This study investigated the retinotopic functional representation in the visual cortex of mild to moderate primary open-angle glaucoma (POAG) participants and age-matched normal volunteers, using wide-view visual presentation, high-resolution retinotopic stimuli, and high-resolution blood oxygenation level dependent (BOLD) functional magnetic...

Glaucoma diagnosis with spectral-domain OCT of GCL and IPL

This is a prospective, cross-sectional, observational study by the New York Eye and Ear Infirmary, which recruited normal subjects and glaucoma patients with a range of visual field loss representing various degrees of glaucomatous optic neuropathy. A total of 69...

Chronic lymphocytic leukaemia (CLL) of the lacrimal sac

The authors present a case series of three patients with known CLL, two of which presented with mass and epiphora and one case with epiphora alone. All three patients had initially being diagnosed and were treated for chronic dacryocystitis. Histopathological...

Preoperative RPE alterations in macular holes

This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...

Rituximab efficacy for juvenile idiopathic arthritis

This is a retrospective study about the long-term efficacy of rituximab in patients with severe juvenile idiopathic arthritis (JIA)-associated uveitis. A total of eight patients (15 eyes) were recruited in this study in a single tertiary referral centre from Italy....

Lacrimal gland carcinoma

This is a major review of the management of lacrimal gland carcinoma, focusing mainly on adenoid cystic carcinoma. Relevant literature published in English since 1970 was included amounting to some 40 articles after filtering. Overall mortality for all lacrimal gland...

Do occult neuroretinitis and non-arteritic anterior ischaemic optic neuropathy differ in presentation?

This study evaluates differences between neuroretinitis and non-arteritic anterior ischaemic optic neuropathy (NAAION) in terms of patient demographics, clinical presentation, and optical coherence tomography (OCT) findings. Medical records of patients with a final diagnosis of occult neuroretinitis or NAAION were...

Inverted internal limiting membrane flap vs internal limiting membrane insertion technique for large macular holes

This meta-analysis aimed to compare and evaluate the morphological and functional outcomes between the inverted internal limiting membrane (ILM) flap and ILM insertion techniques in the treatment of large macular holes (MHs). The primary outcome measures were defined by the...

Comparison of ketorolac 0.4% and nepafenac 0.1% for the prevention of CMO after phacoemulsification

This is a prospective randomised clinical trial study including patients older than 40 years with age related cataract and normal ophthalmic examination. The patients are randomised into three different groups and the objective of the study is to compare the...