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1757 results found

Wide variation in the volume of the sphenoid trigone

This is a radiological study of the volume of the sphenoid trigone in normal subjects. The authors were interested to see how much volume could be gained by removal of the trigone during an orbital decompression for thyroid eye disease....

Is an increased homocysteine level associated with greater risk of AMD?

Basic research studies have implicated homocysteine in causing vascular endothelial dysfunction and inflammation, and this has been borne out in large observational studies which suggested that elevated homocysteine is associated with increased risk of cardiovascular disease. In order to determine...

Risk factors for NTG in a young Korean population

Previously known ocular and systemic risk factors for normal tension glaucoma (NTG) include myopia, peripapillary atrophy, disc haemorrhage, migraine, obstructive sleep apnoea, thyroid disease and cerebral infarction. However, most NTG risk factor studies have examined patients aged 40 years and...

Comparison between findings in ‘active’ or ‘healed’ giant cell arteritis

Giant cell arteritis (GCA) is the most common systemic vasculitis in older people and can cause devastating sight loss if untreated. Temporal artery biopsy is often relied upon for diagnosis by ophthalmologists, with a positive biopsy result indicating whether the...

Association of strabismus with functional impairment in children in the USA

In this study the authors aimed to (1) determine if strabismus is associated with clinically significant functional impairment, (2) identify specific domains of impairment and (3) examine predictors of impairment among children aged 5-17 years. Data were extracted and analysed...

Clinical predictors of proliferative sickle cell retinopathy

Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...

The risk factors associated with isolated microvascular third nerve palsy

The authors used the Rochester Epidemiology Project for this retrospective case review of third nerve palsy. Inclusion criteria was adults >18 years, with new onset isolated microvascular third nerve palsy diagnosed within a 36-month period, with recovery or significant improvement,...

Diagnostic error rates for ROP detection by trainee ophthalmologists

The purpose of this study was to characterise common errors in ROP diagnosis by ophthalmologists-in-training in the USA and Canada. Case acquisition was from a web-based system used for ROP assessment from which 20 cases were selected. Fifty-five trainees from...

Diagnostic error rates for ROP detection by trainee ophthalmologist in middle-income countries

The purpose of this study was to describe errors in ROP diagnosis made by ophthalmologists-in-training from programmes in middle-income countries including Brazil, the Philippines and Mexico who participated in a tele-education programme. Trainees were tested on 20 cases from a...

Glaucoma UK offers up to £50,000 for the Open Call Research Award 2024

Glaucoma UK accepts applications for the Open Call Research Award 2024, which offers up to £50,000 in funding for glaucoma-related research. This award invites both clinical and non-clinical researchers who aim to enhance our understanding of glaucoma, and improve outcomes for people living with the disease.

VEGF and axial length (RVU)

The authors of this paper set out to examine whether the concentrations of VEGF in the vitreous were associated with refractive error and axial length in eyes without retinal disease, except of macular holes or epiretinal membranes. A vitreous sample...

Precision and accuracy of TearLab osmometer

Measuring tear osmolarity has been identified as a potential method for objectively diagnosing dry eye. TearLab osmolarity system is an in situ osmometer which may be a promising candidate for clinical use as it is portable and only requires a...