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Molecular genetics of achromatopsia

Achromatopsia is a rare autosomal recessive disorder of the cone photoreceptors. Typical characteristics of affected patients include the inability to distinguish colours, impaired visual acuity, photophobia and nystagmus. The condition is said to be more frequent in the Pingelapese population...

The management of chronic uveitis

A 40-year-old company executive is referred from another unit with recurrent anterior and posterior uveitis for 12 months and the inflammatory markers are raised. Review of systems This is a case of chronic uveitis which needs a thorough workup and...

Corneal stroma modelling under hypoxic conditions

The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...

Real world results of cataract surgery in pseudoexfoliation

In this single-centre retrospective cohort study, the data of pseudoexfoliation (PXF) patients undergoing phacoemulsification cataract surgery from January 2010 to December 2019 was analysed in the National Health Service setting. The study comprised 23,329 eyes of 15,257 patients. Patients with...

Dead bag syndrome: a new and rare cause of late IOL dislocation

The dead bag syndrome has recently been described as a cause of late spontaneous intraocular lens (IOL) subluxation and / or dislocation. The capsular bag remains clear years after surgery and then becomes diaphanous and floppy. The authors explanted seven...

Surgery technique for subluxation in Marfan syndrome

The authors evaluated the efficacy and safety of bimanual capsulorrhexis combined with sutureless scleral-fixated IOL implant in children with Marfan syndrome. Seven children (14 eyes) with subluxated lenses underwent bilateral surgery; four female, three male with mean age of 7.1...

Endothelial keratoplasty (EK) with anterior chamber intraocular lens (ACIOL) versus secondary posterior chamber lens (PCIOL)

This is a retrospective study of 82 eyes (23 ACIOL, 59 PCIOL) with a history of either pseudophakic (PBK) or aphakic (ABK) bullous keratopathy, who had descemet stripping automated endothelial keratoplasty (DSAEK) with retained or secondary ACIOL, or DSAEK with...

Impact of COVID-19 pandemic on US paediatric ophthalmology

The authors designed and distributed a survey to assess the economic impact of the pandemic on US paediatric ophthalmologists over the sustained lockdown period of 18 months in 2020/21. They captured information on clinical and surgical revenue, staff hiring and...

The results of the last survey Oct21

This edition’s survey questions moved away from the deep and ethically charged questions of the recent surveys and focussed on simple and straightforward issues. This is really where the surveys began in exploring the minor practice variations which we have...

Insights in resistant diabetic macular oedema

This article gives a bird’s eye review of the different modalities for the treatment of diabetic macular oedema (DME). The debut of anti-VEGFs has brought a paradigm shift in DME management. This treatment has now become a major breakthrough in...

Primary eye health care in low- and middle-income countries

The need for eyecare services in low- and middle-income countries Recent global estimates (2020) suggest that there is more than a three-fold difference in the prevalence of all categories of visual loss (presenting visual acuity <6/12 in the better eye)...

Clinical and management strategies in glaucoma practice: perspectives from international glaucoma specialists

Management options and outcomes in glaucoma practice were reviewed at the 7th Moorfields International Glaucoma Symposium, held in London on 24 January 2015. This article summarises perspectives from international glaucoma specialists on debated issues in topical therapy, glaucoma surgery, diagnostic...