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Acute comitant esotropia as the presenting sign of diffuse intrinsic pontine glioma

The authors present four children with acute comitant esotropia (AACE) associated with diffuse intrinsic pontine glioma. All were treated with radiation therapy and all subsequently died due to the tumour. Children were aged 5, 5, 4.5 and 11 years. General...

Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Choroidal and RNFL thickness in patients with OSAS

In obstructive sleep apnoea syndrome (OSAS), hypoxia secondary to repetitive apnoeic episodes leads to blood pressure variations and haemodynamic changes. There is also intermittent activation of the sympathetic system when the patient is aroused from sleep during apnoeic episodes. OSAS...

Macular thickness and visual fields

The authors describe a comparison of spectral domain OCT with Humphrey visual fields (HVF) mean deviation (MD) and pattern standard deviation (PSD), examining the retinal thickness of the macula and circumpapillary retinal nerve fibre layer (RNFL) defects. Seventy-three subjects who...

Defining of a successful surgery for different types of strabismus

The authors present the results of a Delphi study, following on from their previous work which defined successful general outcomes for strabismus surgery. This study aimed to define success outcomes for specific types of strabismus. Twenty-five experts were involved in...

Spot screener versus Grand Seiko measurements

The authors aimed to determine repeatability and reproducibility of refractive values and pupil size measured using the Spot Vision Screener and to compare its measurement values with the Grand Seiko autorefractor. This was a cross-sectional study of 22 healthy adults;...

Avoiding investigations through history taking and examinations to differentiate serious from comparably benign aetiology

*Joint first authors. Introduction Anisocoria can be a sign of neurological deficit, necessitating numerous investigations [1]. This case report explores how expensive and time-consuming investigations can be avoided by thorough history taking and examination to differentiate serious from comparably benign...

Ophthalmology history and examination – a guide for medical students

*First author Students have very little exposure to ophthalmology during their years at medical school. Teaching consists of a handful of lectures followed by a short placement in which students are expected to practise histories and examinations on patients with...

Moorfields earns UK’s first UKAS accreditation for ophthalmic and vision science (IQIPS)

The United Kingdom Accreditation Service (UKAS) has granted the first accreditation for Ophthalmic and Vision Science to Moorfields Eye Hospital. The award was made to the Electrophysiology Department at Moorfields under the Improving Quality In Physical Services (IQIPS) programme.

Excel tips

In previous articles Microsoft Outlook and OneNote have been the focus. Here, it is Microsoft Excel that gains the spotlight. Excel is a powerful tool, likely known, at least to a basic degree, to all readers. Below are walkthroughs of...

Agreeing terminology for non-classic visual field abnormalities

The authors present a prospective survey of neuro-ophthalmologists. The survey comprised of 10 visual fields. The selection of visual fields for the survey aimed for variety and excluded classic neuro-ophthalmology visual field defects, e.g. hemianopia, nasal step. The survey was...

Keratoconus: Diagnosis and Management

From the history of keratoconus to its diagnosis and management, this book covers everything. Don’t be fooled by thinking keratoconus is a simple disease like I did; this book is dense, and packed with information. The book is divided into...