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Ovarian hormones drive onset of Sjogren’s disease in mice

Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...

Optic nerve swelling – your survival guide (part 2)

In this second article we will discuss bilateral optic nerve swelling, its aetiology, various investigations and possible treatments. We will also discuss various protocols used in the management of suspected optic nerve swelling cases. (Part one of this topic available...

Improved efficacy expected with second-generation microinvasive glaucoma surgery (MIGS) devices

Microinvasive surgical approaches to primary open-angle glaucoma (POAG) offer minimally traumatic options for effective intraocular pressure (IOP) reduction in appropriately selected glaucoma patients. Increases in laser trabeculoplasty rates and wider adoption of glaucoma drainage device filtration procedures, together with the...

Doctor by the sea (Pete’s Hidden Curriculum Part 1)

See Pete's Hidden Curriculum Part 2 here. “They can always hurt you more.” This is The Fat Man’s Law Number 8 from the book The House of God by Samuel Shem. For those that have not read this book, it...

Acute macular neuroretinopathy

Acute macular neuroretinopathy (AMN) is a rare condition that typically affects young women and presents with photopsia and paracentral scotomata [1]. We describe a case of severe acute macular neuroretinopathy, following Covid-19 infection. A 30-year-old woman presented to the urgent...

Microbiology, risk factors and outcomes of microbial keratitis in Sydney, Australia

The authors present a retrospective case series including all patients with microbial keratitis and ocular surface diseases (OSD), including dry eye, blepharitis, Stevens-Johnson syndrome and / or ocular cicatricial pemphigoid, over a five-year period between 2012 and 2016. A total...

Four year outcomes of macular degeneration treated with ranibizumab

The authors report on a retrospective study of neovascular age-related macular degeneration (AMD) patients treated with a variable ranibizumab dosing regimen over a period of four years (from January 2007 to December 2011). A total of 600 treatment naïve eyes...

Bupivicaine injection for Bell’s palsy

This study assesses the use of intramuscular bupivicaine to treat lid retraction and lagophthalmos in facial palsy. It is a prospective non-comparative interventional series of 10 patients with Bell’s palsy (House-Brackman grade IV or V) who each received three serial...

Predictive measure for alignment stability

The authors aimed to determine whether a correlation exists between the immediate operative alignment and future alignment in fixed suture strabismus surgery. This study enrolled 54 patients; seven were lost to follow-up so results are presented for 47 cases. Mean...

Orbital abscess following posterior subtenon steroid injection

The authors report a case of orbital cellulitis following posterior subtenon injection of triamcinolone acetonide. A 57-year-old male patient with a background of complicated cataract surgery underwent vitrectomy with explantation of dislocated intraocular lens and insertion of anterior chamber lens....

A case report of papilloedema caused by unilateral jugular vein thrombosis

In rare cases, unilateral jugular vein thrombosis can lead to increased intracranial pressure and papilloedema, resulting in headaches and visual loss. The authors describe the case of a 45-year-old patient with squamous cell carcinoma of the larynx who developed right...

Conversion to strabismus and amblyopia

This study was undertaken to evaluate the incidence of true manifest strabismus, the visual acuity at school screening and whether risk of failing screening is different in those discharged at first visit or followed up. The author reviewed 248 children...