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Exploiting nature’s randomised trials of eye disease

Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...

What you learn after performing 10,000 cataracts

What do you do when the anterior chamber shallows, or the zonules give way? How do you handle the stubborn epinuclear plate? Raymond Radford shares the benefit of his experience when dealing with tricky cataract surgery. Firstly, you realise you...

Traumatic optic neuropathy

In neuro-ophthalmology we get asked a lot about management of patients who suffered significant trauma and presented with loss of vision secondary to presumed traumatic optic neuropathy (TON). TON happens usually in the context of significant craniofacial trauma. The incidence...

Birdshot chorioretinopathy: an important differential

Birdshot chorioretinopathy (BSCR) is a relatively uncommon cause of posterior uveitis which often has a relapsing and remitting course [1,2]. We present a case which demonstrates how remission can be obtained for several years using cyclosporine. Case report A 44-year-old...

Acute dellen formation post trauma

Corneal dellen are saucer-like thinnings, usually of the peripheral cornea [1]. Dellen formation is thought to be related to localised tear film instability [2], specifically the absence of the mucin component of the tear film. Without the mucin layer, dry...

Can OCT predict Alzheimer’s disease?

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Can OCT predict Alzheimer’s disease? In 1986 Hinton et al. demonstrated evidence of optic nerve degeneration...

“I can’t see nothing out of that eye, you ....!”

This is exactly the call you don’t want to receive at 11 at night. The A&E colleague phoned to inform me about a young man who was kicked several times in the face and could not see out of one...

What’s Eating Gilbert Pete

“Please phone Mr C Lyon ASAP on 0131 334 9171” This was a message from my secretary waiting for me on my computer one morning shortly after I was appointed a consultant. The name did not ring any bells but...

Getting the Duke Elder examination right: reflections and tips from a medical student

The Duke Elder undergraduate prize examination is an annual exam organised by the Royal College of Ophthalmologists in the United Kingdom. Named after Sir Stewart Duke Elder, a prominent British ophthalmologist, the exam is designed to encourage undergraduate medical students...

Human factors in the operating room

The importance of minimising human error in surgery is well established. This was initially sparked by lessons learned from the aviation industry in the 1970s after several fatal flight accidents [1]. This became a catalyst for a movement on training...

Running a high-volume nurse led intravitreal service using the Sp.eye device – the Stanley Eye Unit experience

Introduction The vast majority of ophthalmology units utilise allied healthcare professionals (AHPs) to deliver intravitreal injections (IVIs). The Royal College of Ophthalmologists issued a statement 10 years ago advocating the use of non-medical practitioners performing IVIs [1]. The main benefit...

Useful, interesting, or maybe both

This column is often, but not always, about ophthalmic tech. This is one of those ‘not always’ editions. Time to share some interesting or useful things from the internet which can help in a number of ways, from preparing presentations...