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Randomisation, confounding & observational methods in ophthalmic epidemiology
Randomisation and confounding Understanding the relationship between an exposure and an outcome of interest is the central challenge in ophthalmic epidemiology. The exposure may be aetiological, taking the form of a putative risk biological factor, or therapeutic, in the form...Getting the Duke Elder examination right: reflections and tips from a medical student
The Duke Elder undergraduate prize examination is an annual exam organised by the Royal College of Ophthalmologists in the United Kingdom. Named after Sir Stewart Duke Elder, a prominent British ophthalmologist, the exam is designed to encourage undergraduate medical students...Psychiatric Consequences of Ophthalmic Disease
In part two of this series on ophthalmology and psychiatry, the authors will cover the possible psychiatric consequences of ophthalmic disease. The following conditions will be discussed: a. Black patch psychosis b. Psychological state in blindness c. Phobias in the...Lost in translation
The article that follows is a collection of reflections and observations by Peter (British) and Nathan (Singaporean) living and working in each other’s countries. Peter Cackett “Best thing about this place is it’s not still full of pompous ex-colonials who...Cutting-edge practice in glaucoma care: what, how and why?
More effective treatments and drug delivery modalities, implantable minimally invasive glaucoma surgical (MIGS) devices, as well as accelerating clinical research programmes, will transform the surgical and clinical management of glaucoma in the near future. There is also an ever-greater emphasis...Quiz Apr/May 2023
History A 76-year-old female presented at her local district general hospital with right decreased visual acuity, glare, and foreign body sensation, in addition to longer-term dry eyes. She was otherwise well. Her past medical history included hypertension. On examination: vision...
Retinoblastoma risk factors for recurrence
This study evaluates risk factors for local tumour recurrence of main solid tumour, subretinal seed, vitreous seed and new tumour formation in eyes with retinoblastoma (RB) management with primary chemotherapy over 20 years of follow-up. The study included 960 eyes...
Does paediatric rhegmatogenous retinal detachment (RRD) obey Lincoff’s rule (LR)?
This was a retrospective study where 98 paediatric patients with RRD were identified through surgery records. Forty case sheets with complete record of ocular examination and surgical findings were analysed. Visible or suspected preoperative retinal break identified using the LR...
VKH outcomes with pulse IV steroids
This is a retrospective review of clinical case notes records of 111 Vogt-Koyanagi-Harada (VKH) patients between 1999 and 2015 from a single centre in Tokyo, Japan. The mean age at presentation was 41 years and the median follow-up period was...
Metamorphopsia in idiopathic epiretinal membranes
The Amsler grid is commonly used for self-monitoring, but is qualitative and has low sensitivity. The M-chart reduces the amount of spatial redundancy (‘filling in’) in the Amsler grid. The Orientation Discrimination (OD) test studied in this paper consists of...
OCTA in angioid streaks
This paper reports on the optical coherence tomography angiography (OCTA) features of choroidal neovascularisation (CNV) secondary to angioid streaks and the ability to predict CNV activity. A total of 38 eyes of 19 patients were included in the study. Thirty...
