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Treatment of Sjogren’s Syndrome dry eye in mouse model
Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...A step-by-step approach to the diagnosis and management of Sands of Sahara Syndrome
Sands of Sahara syndrome (diffuse lamellar keratitis) is a rare postoperative complication of Laser in situ keratomileusis (LASIK). Its estimated prevalence is reported to be 2-4% among LASIK cases [1], despite that, it is more likely to be encountered by...
Adjustment under topical anaesthesia in children
This is a study of 19 cases of strabismus surgery using topical aesthetic and intraoperative adjustment in selected children. The study included 14 males and five females with mean age of 12.68 ±2.5 years (range 8-16). Five were esotropia and...
BT for convergence spasm
The aim of this study was to analyse the response of a cohort of patients with convergence spasm to the injection of botulinum toxin (BT) in the medial rectus muscle. This was a retrospective study of six patients with a...
Importing iron to the retina
In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...
BT as a diagnostic tool in Duane’s retraction syndrome
This study evaluated the effects of botulinum-toxin (BT) on management of Duane’s retraction syndrome along with how BT can be used diagnostically to help with patient expectations and decide management. Functional and psychosocial impact of BT effect was evaluated in...
Sustained elevation of extracellular ATP in chronic glaucoma
Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...
Brn3b neuroprotective effect in rat glaucoma model
An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...Understanding the inequalities of ophthalmic care for Indigenous people in a first world country
Aboriginal Australians have faced numerous challenges over the past centuries. Here in this article, Edward Saxton highlights why there are inequalities of ophthalmic care in Australia and why this has led to increased levels of blindness in Aboriginal people relative...
Intracameral mydriasis with Mydrane
The aim of this study is to evaluate the ‘real world’ experience in a UK setting for intracameral Mydrane mydriasis in routine cataract surgery. A prospective consecutive series of 60 patients (group 2) had intraoperative, intracameral Mydrane (tropicamide 0.02%, phenylephrine...Is this a retinal detachment?
Despite the help of allied health professionals in triaging and managing acute ophthalmic emergencies, eye casualty remains overburdened. Trainees at the beginning of their training often struggle to manage such busy clinics with varied presentations. We present a case that...
