You searched for "VEGF"
Subfoveal choroidal thickness and PCV
1 April 2018
| Saruban Pasu
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Retina / Uvea / Vitreous
This report studies the prognostic factors for visual improvement and the need for additional treatments at one year after the initial combination therapy of intravitreal ranibizumab injection or intravitreal aflibercept injection followed by PDT in eyes with PCV. Fifty-six eyes...
Transfected RPE cells inhibit AMD in rats
1 August 2015
| Graham Wallace
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Retina / Uvea / Vitreous
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Age-related macular degeneration, Choroidal neovascularization, Fibulin-5, Retinal pigment epithelium, Transplantation
Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Wet AMD is characterised by choroidal neovascularisation, new vessels into the retina, leading to leakage and tissue damage. Many proangiogenic factors particularly vascular endothelial growth factor (VEGF)...
Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema
1 April 2015
| Jonathan CP Roos
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Retina / Uvea / Vitreous
Macular oedema (MO) is a leading cause of visual impairment in patients with diabetic retinopathy. Whilst laser photocoagulation therapy has been the proven treatment for decades, studies over the last five years have also established a role for anti-VEGF agents...
Aqueous humour cytokine levels in PCV and nAMD
1 April 2015
| Bheemanagouda Patil
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Retina / Uvea / Vitreous
This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...
Intravitreal dexamethasone implant for diabetic macular oedema
1 February 2015
| Brian Ang
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Paediatric Ophthalmology / Strabismus
The authors report on the three-year outcomes of the Ozurdex Dexamethasone (DEX) intravitreal implant multi-centre trial for the treatment of diabetic macular oedema (DME). Patients with DME (best-corrected vision of 20/50 to 20/200 and central retinal thickness of ≥300µm) were...
A case of ‘60-day glaucoma’
3 April 2023
| Jagruti Godhaniya, Rajan Paul
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Ophthalmology
Neovascular glaucoma (NVG) has been called ‘90-’ or ‘100-day glaucoma’ in the past due to its typical development three months after the onset of central retinal vein occlusion (CRVO). In reality, NVG can occur anywhere between two weeks and two...
What’s new in wet AMD papers?
1 December 2016
| Rod McNeil
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Retina / Uvea / Vitreous
Paper presentations on neovascular (‘wet’) age-related macular degeneration (AMD) from the 16th European Society of Retina Specialists Congress, Copenhagen, September 2016, outline recent research directions evaluating the impact of vision loss on key health domains, patient preferences in the process...
Advances and developments in medical retina
The author provides an update on late breaking clinical trial results in neovascular age-related macular degeneration (nAMD) and presentations on diabetes management from the American Academy of Ophthalmology Retina Subspecialty Day, held during the Academy’s annual meeting in Chicago, October...Diabetes macular oedema in pregnancy self-resolving postpartum
1 October 2021
| Rajesh Deshmukh, Antony Raharja, Li Teng Kok
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Ophthalmology, Retina / Uvea / Vitreous, Imaging
*Equally contributing co-first authors. Diabetic macular oedema (DMO) is a common clinical presentation to ophthalmology clinics. Ample evidence exists for management of DMO in non-pregnant patients. However, there is a paucity of evidence on the optimal management of DMO in...
Twenty-five years in retina
In the next of our articles celebrating 25 years of Eye News, the authors look at how the retina specialty has changed over this time and ask what the future might hold. Retinal disease management has benefited from great advances...Epidemiology of ocular cancer in Cali
The aim of this study was to describe the population trends of incidence and survival rates of ocular cancer in Cali, Columbia. Data was retrieved from the Registro Poblacion de Cancer de Cali (RPCC, i.e. Population Cancer Registry of Cali)...Effect of minor trauma in eyes with previously undiagnosed angioid streaks
1 April 2014
| Balini Balasubramaniam
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AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Oculoplastics, Ophthalmology, Optometry, Orbit, Ocular Pathology and Oncology, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
Angioid streaks (AS) may be associated with pseudoxanthoma elasticum (PXE), Paget’s disease, haemoglobulinopathies, Ehlers-Danlos Syndrome or abetalipoproteinaemia. Histopathology showed retinal pigment epithelium (RPE) and choriocapillaris loss, elastic fibre degeneration, calcium deposition, active choroidal neovascular membrane (CNVM) and vascular endothelial growth...