You searched for "epithelium"
Ranibizumab for the treatment of age-related macular degeneration
1 April 2015
| Nana Theodorou
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Retina / Uvea / Vitreous
This multicentre randomised prospective open label study compared 0.5 versus 2mg of ranibizumab in patients with submacular retinal pigment epithelial (RPE) detachment due to age-related macular degeneration. Four treatment regimens were used for the two strengths either monthly for 12...
Cytotoxic effect of voriconazole on human corneal epithelial cells
Voriconazole is a second-generation synthetic derivative of fluconazole with broadened antifungal spectrum. It is becoming the drug of choice for fungal keratitis. Voriconazole eye drops are not available commercially, thus have to be prepared by diluting the intravenous formulation containing...Doctor prints cornea on demand!
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Doctor prints cornea on demand! Dr Hideo Kodama from the Nagoya Municipal Industrial Research Institute first...Apr/May 2018 Quiz
History A 57-year-old lady presents with a right subconjunctival lesion which has been increasing in size for three months (Figure 1). She has never had vision problems other than presbyopia. Past medical history: hypertension and asthma. On examination, she had...Boosting key protein in eye cells could prevent age-related vision loss, international team finds
Increasing the levels of a key protein in the cells at the back of the eye could help protect against the leading cause of vision loss among older adults, finds a new discovery made by researchers from the UK, US, Germany and Australia.
RPE atrophy onset in treated nAMD
1 October 2019
| Sofia Rokerya
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Retina / Uvea / Vitreous
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Age-related macular degeneration, Aqueous humor, Atrophy, Complement, Vascular endothelial growth factor
In this study the authors aim to evaluate the role of various factors for the development of retinal pigment epithelium (RPE) atrophy over a period of five years in patients with nAMD. Fifty-two newly diagnosed nAMD patients with complete absence...
Results of fixed aflibercept treatment regime in type 3 neovascularisation
1 April 2020
| Sofia Rokerya
|
Retina / Uvea / Vitreous
In this prospective study the authors evaluate the effect of intravitreal aflibercept injections in the treatment of naive type 3 neovascularisation using a fixed treatment regime. Fourteen eyes of 14 patients were studied. All patients were treated with intravitreal 2.0...
Corneal keloid: Report of natural history and Outcome of Surgical Management in Two Cases
Corneal keloids are rare and typically reported following trauma (including post-surgical) and has been reported without any trauma or previous surgery. A corneal keloid differs from a hypertrophied scar in that it occurs months/years after the injury, enlarges over time...Take this waltz
My last weekend on-call was the busiest I can remember for a very long time. We were just completely swamped with patients. The weather was not too good that Saturday and it felt like every second inhabitant of our ocean...
Complement Factor H and Factor H-Like protein are expressed in human RPE cells
1 April 2014
| Bheemanagouda Patil
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Ophthalmology
The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...
Cataract in patients with pseudoexfoliation syndrome
1 August 2018
| Kurt Spiteri Cornish
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EYE - Cataract, EYE - Refractive
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Apoptosis, TUNEL, cataract, lens epithelial cell, pseudoexfoliation syndrome
The authors present a prospective comparative study in 43 patients with (group 1) or without (group 2) pseudoexfoliation (PXF) undergoing cataract surgery. Anterior capsule samples were obtained in all patients and analysed for signs of apoptosis by using special staining...
