You searched for "genetic"
Association between serum 25-hydroxyvitamin D levels and age-related cataracts
1 February 2016
| Sharmina Khan
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Cataract and Refractive
Cataractogenesis occurs as a result of ageing, smoking, exposure to UV radiation and genetic predisposition. Antioxidants can reduce the cataract risk as found in animal models and humans and vitamin D is one of them. This epidemiological study based in...
In conversation with Robert MacLaren
2 December 2019
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Ophthalmology, EYE - Vitreo-Retinal
Professor Robert MacLaren gave the Keeler Lecture at the Royal College of Ophthalmologists Annual Meeting in May 2019 on gene therapy for retinitis pigmentosa. We caught up with him afterwards to find out more. What are the key messages of...
PAX6 methylation and myopia
2 December 2024
| Ian Reekie
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EYE - Vitreo-Retinal
The authors present a case control study of 41 adolescents (age 12–14) with myopia and 39 age- and sex-matched non-myopic controls. The myopic patients were sub-divided into mild, moderate and severe myopia subgroups. DNA was extracted from peripheral blood samples...
The past and the future for paediatric ophthalmology
1 June 2018
| Jane Ashworth, Chris Lloyd (Prof)
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Paediatric Ophthalmology / Strabismus
The past 25 years have seen remarkable advances in clinical eye care for children in the UK. This has led to both improved outcomes and better patient and family experiences. There have been substantial changes to patient pathways, major advances...
Health-related quality of life after cataract surgery
1 June 2016
| Bheemanagouda Patil
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Cataract and Refractive
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cataract, cataract surgery, quality of life, quality-adjusted life years
This prospective study evaluates the impact of cataract surgery on subjects’ health-related quality of life (HRQoL) measured with a 15-dimension generic instrument, the 15D. The HRQoL of cataract subjects was compared with that of an age- and gender-standardised sample of...
Progression of macular atrophy in Stargardt disease
3 April 2024
| Ian Reekie
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Retina / Uvea / Vitreous
The authors present a study of a cohort of patients with genetically proven ABCA4 gene mutation related Stargardt disease. They aimed to quantify the effect of lesion location and topography on disease progression using fundus autofluorescence imaging. One hundred and...
Boosting key protein in eye cells could prevent age-related vision loss, international team finds
Increasing the levels of a key protein in the cells at the back of the eye could help protect against the leading cause of vision loss among older adults, finds a new discovery made by researchers from the UK, US, Germany and Australia.Blind Faith: In Conversation with Mariya Moosajee
16 August 2023
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ONLINE EXCLUSIVE ARTICLES
In light of the BBC releasing Blind Faith: Do genetic eye disease ‘treatments' work? earlier this year, a documentary which follows BBC journalist Ramadan Younes as he investigates practitioners who falsely claim to have ‘treatments’ for genetic eye disease, Eye...
How accurate is the supplement content in both generic and branded ophthalmology supplements?
5 October 2020
| Tasmin Berman
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Retina / Uvea / Vitreous
This prospective cross-section study compared the concentrations of Vitamin C, Vitamin E, Zinc, and Copper in five dietary supplements including both national and regional brands used for macular degeneration in the United States. They performed a comparative analysis using gas...
A paperless future – get involved!
1 August 2014
| David Haider
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AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
Jeremy Hunt’s statement earlier in 2014, about a paperless NHS by 2018, has added momentum to the transition away from paper records. The Tech Review this issue discusses what that will involve and how and why you may want to...
Quality of life after oculoplastic surgery
This is a literature review of published quality of life surveys in patients who have undergone a variety of oculoplastic procedures. The authors emphasise the importance of patient reported outcomes, noting that clinician and patient perceptions may differ, and that...Assessing and treating achromatopsia
1 August 2019
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
This literature review considers clinical characteristics (pendular nystagmus, poor visual acuity, lack of colour vision and marked photophobia), genetics (autosomal recessive disease, with CNGA3, CNGB3, GNAT2, PDE6C, PDE6H and ATF6 gene mutations), diagnostic options (OCT and fundus auto fluorescence), and...