You searched for "ranibizumab"
The Complainers
1 April 2014
| Gwyn Samuel Williams
|
AMD, Emergency Ophthalmology, Genetics, Ophthalmology, Optometry, EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
There she was. Sitting in the waiting room with her arms crossed, tut-tutting to herself and shaking her head mournfully every few minutes. We gazed at her from a safe distance while one of the nurses confirmed what we already...
Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?
1 February 2017
| Usha Chakravarthy (Prof)
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EYE - Vitreo-Retinal
There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...
Corporate M&A pace gathers momentum
1 October 2019
| Rod McNeil
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AMD, Emergency Ophthalmology, Genetics, Ophthalmology, Optometry, EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...
Myopic choroidal neovascularisation
1 August 2015
| Jonathan Chan
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Retina / Uvea / Vitreous
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Neovascularisation, Retina, Treatment Medical
This is a review article summarising the latest myopic CNV (choroidal neovascularisation) literature in the clinical experience and management outcomes for recommendation algorithm. The aetiology of the myopic CNV was discussed by the authors under the heading of the heredo-degenerative...
Combined anti-VEGF and PDT for wet AMD
1 February 2014
| Brian Ang
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Retina / Uvea / Vitreous
The authors report on a retrospective case series of combined anti-VEGF and photodynamic therapy (PDT) in the treatment of wet age-related macular degeneration (AMD) refractory to anti-VEGF monotherapy alone. The criteria for treatment failure of anti-VEGF monotherapy were persistent subretinal...
Cutaneous malignant melanoma metastasis to pseudophakic lens
4 February 2021
| Annes Ahmeidat
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Ocular Pathology and Oncology
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Cutaneous melanoma, Diagnostic vitrectomy, Granulomatous inflammation, Malignant melanoma, Metastasis, Posterior capsule, Uveitis
Metastases to the eye and orbit are rare and intraocular cutaneous malignant melanoma metastasis (ICMM) is exceedingly rare, representing around 5%. There have only been three previous cases of ICMM to the lens in the literature, all of which presented...
OCT biomarkers in asymmetric anti-VEGF response in bilateral diabetic macular oedema
1 December 2021
| Su Young
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Retina / Uvea / Vitreous
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Diabetic macular edema, aflibercept, optical coherence tomography, predictive, ranibizumab
This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular oedema (DMO). Bilateral DMO patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab / aflibercept) treatment were retrospectively studied....
Effect of anti-VEGF treatment on PED morphology
1 June 2015
| Jaya Myneni
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Retina / Uvea / Vitreous
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Choroidal neovascularization, optical coherence tomography, ranibizumab, VEGF
This retrospective study of 30 eyes assessed the effect of anti-VEGF on morphology of pigment epithelial detachments (PED) secondary to age-related macular degeneration (AMD). Thirty eyes of 28 patients with PED were compared to 30 eyes of 30 patients with...
Aqueous humour cytokine levels in PCV and nAMD
1 April 2015
| Bheemanagouda Patil
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Retina / Uvea / Vitreous
This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...
Belfast briefing: Retina Day roundup from the RCOphth 2024 Annual Congress
2 August 2024
| Rod McNeil
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Ophthalmology
Belfast hosted this year’s Royal College of Ophthalmologists’ (RCOphth) Annual Congress, a meeting dedicated to sharing advances, knowledge and clinical practice points in ophthalmic care. This article summarises selected talks by medical and surgical retina specialists during the Retina Subspecialty...
Pathological myopia: a trainer’s perceptive
3 April 2024
| Anitha Priya Arun Shankar, Adelehin Ijasan
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EYE - Vitreo-Retinal
High myopia is defined as myopic refraction of greater than -6 dioptres with an axial length greater than 26.5mm, while pathological myopia is myopic refraction with posterior pole degeneration [1]. These degenerative changes can affect a young population and in...
Endophthalmitis after intravitreal injections in France
1 June 2015
| Efrosini Papagiannuli
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Retina / Uvea / Vitreous
In this nationwide, retrospective, multicentre case series, the authors looked at the incidence and characteristics of endophthalmitis after intravitreal injections of anti-VEGFs and steroids, given for a variety of posterior segment conditions (macular oedema secondary to diabetes or retinal vein...