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Breakthroughs in the genetics of angle-closure glaucoma
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...Diary from my elective: a Parisian experience
The author explains how a research institute’s dedication to multidisciplinary collaboration helped him to discover a passion for academic ophthalmology. The elective aspect to the final year of a medical degree, through its change of scenery and immersion into another...High quality retinal image grading and management service by the NetwORC UK
In 2004 a network of three ophthalmic reading centres in Belfast, London and Liverpool (known as NetwORC UK) was established to form the largest reading centre in Europe for the purpose of providing high quality grading of ophthalmic images for...Ophthalmology assessment using Revised Bloom’s Taxonomy
Bloom’s Taxonomy is a hierarchical list of attributes and skills that facilitates teachers to effectively teach, whilst concurrently enabling learners to effectively learn. It was first developed in 1956 by Benjamin Bloom, an educational psychologist along with a team of...The Global Vision Database
The overall goal of the Global Vision Database (GVD) [1] is to develop and deploy new and improved evidence on the prevalence of blindness and vision impairment (VI) globally. It is a repository which allows us to assess the causes...Glaucoma UK’s campaign raises awareness of glaucoma through people’s unique glaucoma stories
Glaucoma UK is marking Glaucoma Awareness Week 2023, which will run from 26 June to 2 July 2023.
New mouse model of diabetes mellitus
Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...Prevalence of acute anterior uveitis in diabetic patients attending diabetic eye disease clinics
The authors share their investigation at Manchester Royal Eye Hospital into the association between diabetes and AAU. The global prevalence of diabetes mellitus (DM) is rapidly rising from an estimated 9.3% in 2019 to 10.2% by 2030 [1]. The link...
Association of dry eye symptoms in patients with dyslipidaemia and statin use
This retrospective analysis of the Blue Mountains Eye Study III cohort (Caucasian Australians residing west of Sydney n=1680; mean age >74 years, range 60-97) analysed the association between dyslipidaemia, use of oral statins and symptoms of dry disease (DED) among...
Importing iron to the retina
In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...
