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Regulatory drug evaluations and expedited review initiatives: EU and US perspectives

1 April 2016 | | Cataract and Refractive, Cornea / External Eye Disease, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...

The paediatric cataract: an overview of the embryology and pathophysiology

5 February 2020 | | Ophthalmology, Paediatric Ophthalmology / Strabismus, Cataract and Refractive
In the first of the two articles (see Part 2 here) on paediatric cataracts, Samuel Aryee reviews the aetiology of this condition. Cataracts arise from opacification of the natural transparent lens, which can cause partial or total blindness. Although the...

What's trending Apr/May 2019

1 April 2019 | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
#JessicaStarr #suicide This Detroit meteorologist committed suicide in December 2018 following SMILE corrective laser refractive surgery back in October 2018. Small incision lenticule extraction (SMILE) is an alternative technique of laser refractive surgery with different advantages and disadvantages compared to...

Intracameral antibiotics in cataract surgery: current evidence base

1 August 2019 | | Ophthalmology, Cataract and Refractive
Following on from our recent online survey*, the authors examine the use of intracameral cefuroxime as the standard of care in cataract surgery. Cataract extraction with intraocular lens implantation is one of the most frequently performed surgical procedures in the...

Acute management of retrobulbar haemorrhage

1 February 2022 | | Ophthalmology, Orbit, Oculoplastics, Emergency Ophthalmology
The authors discuss the importance of rapid diagnosis and correct management of acute RBH presentation to avoid the risk of permanent blindness. Retrobulbar haemorrhage (RBH) is an ocular emergency that occurs due to arterial bleeding in the orbital cavity behind...

Advances in cataract surgery

1 April 2018 | | Cataract and Refractive
This article covers recent clinical findings in mydriasis and anaesthesia for cataract surgery, shared by Sathish Srinivasan and Keith Davey at a surgical meeting in Manchester. Towards dropless cataract surgery Day case cataract surgery is the standard of care in...

Biometry and IOL choice errors

1 April 2018 | Cataract and Refractive
In the next instalment of this series I focus on problems associated with biometry and intraocular lens (IOL) selection for cataract surgery. I have taken previous medicolegal cases I have dealt with and tried to extract some learning points and...

A Multidisciplinary Approach to Neovascular Glaucoma in a Patient with Waldenström’s macroglobulinemia

1 December 2013 |
An 84-year-old Caucasian male attended eye casualty with a four month history of reduced vision, a dull ache and photophobia in both eyes. He had also reported dizziness, weakness and intermittent epistaxis in the nine months prior to presentation. There...

The approach to trabeculectomy postoperative complications

1 August 2016 | | Glaucoma
Performing a trabeculectomy is like giving birth to a baby. It may be traumatic and there is scope for devastating error but once the operation is completed only then does the real work begin. The bleb must be nurtured into...

Development of retinoblastoma care in Indonesia and the role of multidisciplinary team meetings

4 August 2021 | | Ophthalmology, Paediatric Ophthalmology / Strabismus, COVID-19, Retina / Uvea / Vitreous
In the second article of a two-part series (See Part 1 here), the authors focus on the diagnosis and management of retinoblastoma in Indonesia. COVID-19 doesn’t get thanked for many things, but on 19 December 2020 as the world grew...

Mastering clinical skills in ophthalmology

3 October 2022 | | Ophthalmology
To young junior doctors, and some senior doctors who may not have had much exposure to ophthalmology, the specialty can seem very foreign. Not only are the conditions and examination findings specific to the eyes, but the skill set required...

Macula re-attachment following intravitreal ranibizumab in rhegmatogenous retinal detachment

1 February 2015 | | Ophthalmology, Retina / Uvea / Vitreous
Ranibizumab (Lucentis) is a vascular endothelial growth factor inhibitor (anti-VEGF) used for treatment of choroidal neovascular membrane [1]. We report a case where macula off inferior rhegmatogenous retinal detachment was misdiagnosed as wet age-related macular degeneration (AMD) and three intravitreal...