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2495 results found

Gender and ethnicity related differences in optic nerve head

The authors investigated the effect of ethnicity and gender on optic nerve head morphology comparing Indian and Caucasian males and females. The optic nerve head was investigated using spectral-domain optic coherence tomography (SD-OCT). Results showed that disc and rim areas...

Congenital aniridia clinical features

In this study the authors investigated the various ocular and systemic features associated with congenital aniridia in Indian eyes (262 eyes of 131 patients). The median age at time of first hospital visit was eight years (one day to 73...

MicroRNA mediate retinoblastoma signal transduction

MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...

Ocular characteristics in Marfan syndrome

Marfan syndrome (MFS) is a genetic disorder with clinical manifestations associated with cardiovascular, ocular and skeletal organ systems. Typical signs are descending aortic root aneurysms, ectopia lentis, tall stature and scoliosis. This observational study looked at the ocular characteristics, visual...

Translucent vs. lightproof occluders

This study investigates the change in visual acuity following occlusion in amblyopes and non-amblyopes using translucent versus lightproof occlusion of the dominant eye. Group 1 non-amblyopes consisted of 26 subjects: 16 visually normal and 10 strabismic or anisometropic subjects without...

HtrA1 enhances cell senescence

A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...

Nanoparticle administration of latanoprost

Glaucoma is a progressive optic neuropathy characterised by increased ocular pressure and loss of retinal ganglion cells. Conventional drug therapy with eye drops to reduce intraocular pressure (IOP) has variable bioavailability and can lead to ocular surface disease. In this...

Oral proton pump inhibitors in macular degeneration patients

The authors report five patients with advanced wet macular degeneration and poor vision with onset or enhancement of visual hallucinations with the use of proton pump inhibitors for heartburn management. The hallucinations were reversible with discontinuation of medication. The authors...

Space age surgery

I asked to do theatre lists at Moorfields as part of my timetable. The medical retina fellow jobs are a bit odd in that the vast majority of the different rotations lack a regular theatre session. This might suit some...

From the seas to OCTs, a journey from working in TV to creating teaching in ophthalmology

To relaunch our Allied Professionals section, Paul Dimmock from Gloucestershire discusses his unique role with the Gloucestershire Retinal Education Group. In Gloucestershire we have a collection of ophthalmic-targeted departments led by Professor Peter Scanlon, Clinical Director of the NHS Diabetic...

Telemedicine retinopathy of prematurity (ROP) screening

The Auckland Regional Telemedicine ROP network utilises wide-field digital imaging for ROP screening. Results are from 2006-2015; 1181 infants were screened over three neonatal intensive care units; 83 infants with ROP were identified. Screening rates increased over the 10 years...

A paperless future – get involved!

Jeremy Hunt’s statement earlier in 2014, about a paperless NHS by 2018, has added momentum to the transition away from paper records. The Tech Review this issue discusses what that will involve and how and why you may want to...