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γδ T cell depletion does not affect fungal keratitis

Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...

IO surgery

The purpose of this paper was to evaluate the efficacy of a new surgical technique in reducing inferior oblique muscle overaction (IOOA) consisting of suturing the muscle to the sclera at the Gobin point with tendon sparing and using a...

Macular pigment in relatives of AMD patients

Blue light causes photo-oxidative retinal injury and macular pigment (MP), with lutein, zeaxanthin and mesozeaxanthin as the main components, as a filter that protects the macula from this damage. Previous studies indicated that low levels of macular pigment optical density...

Identification and diagnosis of thalamic haemorrhage

This paper presents a case of thalamic haemorrhage and discusses clinical findings, providing valuable insight into signs clinicians need to look for. The case presented is of a 76-year-old female who developed left hemiplegia and hemi anaesthesia. Ocular motility testing...

A ciliary body tumour

The authors describe a case report of a 60-year-old woman found to have advanced angle closure glaucoma in her right eye and appositional closure of half of the left eye and no glaucoma. The patient had previously undergone two trabeculectomies...

Enzymatic clearance of anterior chamber infiltrate in uveitis

Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...

HtrA1 enhances cell senescence

A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...

A modified technique for external DCR

The authors described a modified technique for external dacryocystorhinostomy (DCR) whereby the lacrimal sac is excised medially along its length using a 15mm blade. Following insertion of silicone stents, the remaining part of the anterior wall of the lacrimal sac...

Designing ophthalmology services Part 3: How do we address the queues post‑COVID-19?

Part 1 of this series available herePart 2 of this series available here There is going to be enormous demand on ophthalmology services as they start to welcome patients back. The authors explain how modelling can help make the most...

Things I’d tell my medical school self, had I known my first year on the job would be during a global pandemic

In a conversation with his younger self, a foundation doctor reflects on the contrast between his expectations of medicine at university and the reality of working during the coronavirus pandemic. Every doctor arrives at medical school with nervous anticipation, yet...

Envision Glasses – A different take on a sight impairment wearable (part 2)

This is the second part of the review of the Envision Glasses (see Part 1 here), a wearable piece of assistive technology. Features From the main menu four feature modes can be chosen: Read, Identify, Find and Call. The Glasses...

Surgical treatment of high myopia

Although several excellent modalities are available for correcting high myopia, the surgical treatment of this condition remains one of the biggest challenges for refractive surgeons; this group of patients is often very dependent on contact lenses. If these patients become...