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Myasthenia gravis presenting with isolated ptosis: a poorly studied subgroup

1 February 2015 | | Retina / Uvea / Vitreous
Investigation into the cause of one isolated symptom or sign can be challenging if that particular sign may be caused by a variety of pathological processes, affecting different tissues, and presenting to different specialties. Unilateral ptosis is a case in...

A paradigm shift in the way we approach cataract surgery

1 February 2015 | | Cataract and Refractive
Cataract surgery is the most common elective surgical procedure in the UK [1], with in the region of 350,000 cases being conducted each year. With an ageing population, this figure will only continue to rise over time. Cataract surgery is...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

1 October 2014 | | Cornea / External Eye Disease
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Eye Capacity: clinical need should drive ophthalmic service provision

1 February 2014 |
Almost two million people in the UK suffer sight loss, a number forecast to double over coming decades. Major causes of blindness are age-related macular degeneration (AMD), glaucoma, diabetic retinopathy, cataract and uncorrected refractive error. Prevalence of these sight-threatening conditions...

An introduction to research governance

1 February 2014 |
Research is the process of acquiring new generalisable knowledge and should be fully integrated into health care work. There is a growing drive to encourage and further develop evidence-based practice in ophthalmology so that staff and patients benefit from improved...

The management of retinal vein occlusions: a summary

1 February 2015 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Imaging, Ophthalmology, Retina / Uvea / Vitreous
Retinal vein occlusions (RVO) are the most common cause of visual loss from retinal vascular disease second to diabetic retinopathy. Vision is lost due to ischaemia, macular oedema and / or haemorrhage which ultimately effects a patient’s quality of life...

A brief history of colour vision

1 April 2019 | | Ophthalmology, Optometry
Andrew Want takes a look at how colour vision has evolved in humans and animals and how it differs across species. Colour vision is something that we often take for granted, but it has become so intrinsic to the way...

Understanding and confronting bacterial endophthalmitis

2 December 2019 | | Ophthalmology, Cornea / External Eye Disease, Emergency Ophthalmology, Retina / Uvea / Vitreous
Abdus Samad Ansari highlights the importance of early recognition of this condition using an unusual presentation. Endophthalmitis is a medical emergency with devastating consequences. Despite adequate treatment, severe cases frequently result in permanent blindness. Endophthalmitis involves inflammation of both the...

The paediatric cataract: an overview of the diagnosis and management

5 August 2020 | | Ophthalmology, Cataract and Refractive
In this second article (see first article here), Samuel Aryee and Rhys Dumont Jones review the challenges involved in managing this condition. Examination and diagnosis Cataracts in children can appear in a variety of forms, each presenting in a different...

The bionic eye – behind the headlines

1 October 2016 | | Oculoplastics, Orbit
Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

3 February 2023 | | Ophthalmology
Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...