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COVID-19 and the eye: a review of ocular involvement and protective strategies
A lot of attention has been placed on the use of face coverings to limit COVID-19 transmission, but there has been less focus on ocular involvement and ocular protection strategies. The author reviews the literature and discusses possible solutions. The...
A case study of posterior globe flattening in idiopathic intracranial hypertension
The authors present a single case of posterior globe flattening without papilloedema in idiopathic intracranial hypertension. The case was a 64-year-old woman with a one-year history of transient visual loss in her left eye only. Visual acuity was 20/20 in...
Cataract extraction and microperimetry
In this study, the authors assessed retinal sensitivity before and after cataract extraction, in an effort to understand how lens opacities may affect microperimetry results in glaucoma and macular diseases. Thirty patients awaiting cataract extraction were examined and their lens...
The posterior capsular rupture rate post COVID-19 pandemic
In this retrospective single centre consecutive case series, the authors investigate the effect of suspending elective cataract surgery during the COVID-19 pandemic for a period of 19 weeks. They divided the study period, September 2019 to January 2021, into three...
Complications after cataract surgery in high myopes: a systematic review and meta-analysis
The authors review all the modern literature on complications after phacoemulsification in high myopes with axial lengths (AL) greater than 25.0mm. Twenty-eight studies reporting on 19,586 eyes were included. The corrected distance visual acuity (CDVA) improved from 0.96 ± 0.53...
Posterior capsular rupture risk factors as reported in the European registry
In this cross-sectional review of the European Registry of Quality Outcomes for Cataract and Refractive Surgery (EUREQUO) including 2,853,376 patients and 31,749 cases with posterior capsular rupture (PCR), the authors observed a trend of reduction in PCR rate from 1.44%...
Knobby eye syndrome
This study used high resolution MRI to demonstrate and evaluate globe shape in axial high myopia and identify and characterise those with prominent equatorial staphylomata that deflect extraocular muscle paths and presumably alter motility patterns in strabismus. The study included...
Sustained elevation of extracellular ATP in chronic glaucoma
Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...
Intravitreal functional plasminogen in branch retinal vein occlusion
Branch retinal vein occlusion (BRVO) is the second most common vascular disorder of the eye. Intravitreal injections of anti-VEGF agents and corticosteroids have proven efficacy. Posterior vitreous cortex (PVC) adhesion has been shown to support the development of retinal vein...Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...
Comparison of SS-OCT and SD-OCT in polypoidal choroidal vasculopathy
Swept source OCT (SS-OCT) is known to have a longer wavelength than spectral domain OCT (SD-OCT), allowing deeper penetration into retinal and choroidal layers. The aim of this study was to investigate whether SS-OCT is superior to SD-OCT in imaging...
