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Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis
This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...
FAZ measurement on OCTA
This paper aimed to test the AngioVue OCTAs reproducibility and interoperator concordance in evaluating the size of the foveal avascular zone (FAZ). The authors also investigated how the FAZs representation on the OCTA varied after metabolic activity. The right eye...Tech supplier search to help tackle 8am rush at GP surgeries
Tech specialists are being sought to help tackle the 8am rush for appointments at GP surgeries.
HLA-B27 anterior uveitis
HLA-B27 has previously been shown to have an association with uveitis, ankylosing spondylitis, reactive arthritis, ulcerative colitis and psoriasis. The authors of this review provide an update of the epidemiology of HLA-B27 associated ocular disorders. There is great variation amongst...
Characteristics of bilateral retinal detachment
This was a retrospective study based at a tertiary centre which analysed the specific characteristics of bilateral Rhegmatogeous detachment, taken from the review notes of 300 patients (600 eyes) who had bilateral retinal detachment (RD) surgery between January 2005 and...
Hereditary profile of retinal detachment
This review sought to clarify some of the heritable elements of rhegmatogenous retinal detachment (RRD). The familial element of RRD is well established, with the sibling recurrence risk ratio being 2.1 (Mitry and colleagues), and the parent-offspring recurrence risk ratio...
Lacrimal gland carcinoma
This is a major review of the management of lacrimal gland carcinoma, focusing mainly on adenoid cystic carcinoma. Relevant literature published in English since 1970 was included amounting to some 40 articles after filtering. Overall mortality for all lacrimal gland...
Froben for anterior scleritis
Flurbiprofen (Froben) is one of the nonselective cyclooxygenase (COX) inhibitors blocking both COX-1 and COX-2 pathways. Agrawal et al. undertook a retrospective cohort study to determine the effectiveness of oral Froben in managing noninfectious, non-necrotising anterior scleritis. One hundred and...
Intravitreal triamcinolone for uveitic macular oedema
This paper from South Korea reports on a prospective, double blind, randomised clinical study designed to evaluate the additional benefit of intravitreal triamcinolone (TA) administration for noninfectious uveitic macular oedema as an adjunct therapy to systemic anti-inflammatory treatment. Patients were...
How common are ocular disorders in the first 12-months of life?
The authors present a retrospective case review of all children aged under one year of age diagnosed with an ocular disorder over a 10-year period. The aim of the study was to describe incidence and types of ocular disorder in...
A comparative treatment study of VCZ and liposomal AmpB in an Aspergillus fumigatus endophthalmitis model
This study aims to compare the effects of voriconazole (VCZ) and liposomal amphotericin B (AmpB) in an experimental model of exogenous Aspergillus fumigatus endophthalmitis in a guinea pig animal model. Endophthalmitis was induced by intravitreal injection of a strain of...
