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1748 results found

SLT versus medication for OAG

This paper appraised existing randomised clinical trials (RCTs), which compared selective laser tabeculoplasty (SLT) with medical therapy for open-angle glaucoma (OAG), and performed a systematic review and meta-analysis. A total of 1229 patients in eight trials were included from PubMed,...

Ultra-widefield fundus autofluorescence

The authors assessed the ease and utility of ultra-widefield fundus autofluorescence (UWF-FAF) in detecting suspected inherited retinal disease in children who were difficult to examine. They aimed to assess the sensitivity of UWF-FAF and UWF-CF (colour fundus) photography and clinical...

Effects of idiopathic intracranial hypertension on the optic nerves

The authors review the latest evidence regarding how the optic nerves are affected by idiopathic intracranial hypertension (IIH), possible pathophysiology and methods of assessment. IIH is described as a clinical syndrome of raised intracranial pressure of unknown aetiology. A systematic...

Large series profiling skew deviation

A retrospective notes review was completed for patients identified as having skew deviation. The authors outline their exact definition of skew deviation within the methods of the paper. One hundred and fifty-seven patients were identified, it is not clear over...

Childhood glaucoma outcomes and prognosis

This study aimed to evaluate the relationship between clinical characteristics and visual acuity in childhood glaucoma. The study included 45 eyes of 31 patients; 33.3% with primary childhood glaucoma and 66.7% with secondary glaucoma; 53.4% of secondary cases had glaucoma...

Visual retraining for homonymous hemianopia following stroke

This is a clinical trial evaluating the efficacy of motion discrimination training as a potential therapy for stroke-induced hemianopic visual field defects involving 48 patients. They were randomised into two arms, one intervention (deficit-field) and one control (sighted-field). Patients were...

Dead bag syndrome: a new and rare cause of late IOL dislocation

The dead bag syndrome has recently been described as a cause of late spontaneous intraocular lens (IOL) subluxation and / or dislocation. The capsular bag remains clear years after surgery and then becomes diaphanous and floppy. The authors explanted seven...

Sebaceous gland carcinoma

This is a review of 241 patients diagnosed with periocular sebaceous gland carcinoma which investigates whether age at presentation influences either the clinical presentation or the outcomes of treatment. Twelve percent of patients were classified as young (<40 years old),...

Outcomes after surgery for INS

The purpose of this study was to detail clinical and electrophysical outcomes after extraocular muscle surgery in adults with infantile nystagmus syndrome (INS). This was a single centre prospective case series of 81 patients aged 18-72 years (mean 36); 63%...

Clinical features and mortality of endogenous panophthalmitis in China

This longitudinal cohort study aimed to report the clinical features, treatment strategy, and mortality of 15 consecutive patients (16 eyes) with endogenous panophthalmitis (EP) at a tertiary medical centre of the largest eye centre in Northern China. Mean age was...

New prognostic model for multiple sclerosis after optic neuritis presentation

The authors present a post-hoc analysis using the publicly available data set from the Optic Neuritis Treatment Trial. The Cox proportional hazards regression models were used to assess for associations between clinical and radiological variables and the development of clinical...

Distribution, progression, and outcomes of inflammatory chorioretinal lesions

This study investigated the distribution and progression of multifocal choroiditis (MFC) inflammatory lesions in 25 eyes of 20 patients and their correlations with clinical outcomes at 24 months. The distribution of choroiditis inflammatory lesions were evaluated semi-automatically using a dedicated...