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Ranibizumab safety in pregnancy
Vascular endothelial growth factor (VEGF) plays a pivotal role during pregnancy, and systemic anti-VEGF administration during this period should thus be avoided. VEGF is expressed in multiple embryonic and foetal tissues during development, with the highest levels found in the...Researchers pursue personalised pathways for glaucoma care
Researchers, funded by Glaucoma UK in partnership with The Royal College of Ophthalmologists, are investigating the potential for personalised glaucoma care by mapping clinical trial data and real-word outcomes to individuals.
Comparison of corneal deformation parameters in keratoconic and normal eyes
This study set out to compare biomechanical properties between normal and keratoconic eyes. It was a retrospective study evaluating 89 eyes (47 normal, 42 keratoconic) and a validation arm of 72 eyes (33 normal, 39 keratoconic) using a high speed...
The natural history of treatment naïve choroidal neovascularisation (CNV) in geographic atrophy
The aim of this retrospective study is to assess the characteristics and natural history of quiescent CNV in geographic atrophy (GA) utilising multi-modal imaging. Case notes were reviewed of patients diagnosed with geographic atrophy between January 2010 and December 2016...
Effects of phacoemulsification on IOP and drug use in glaucoma
For patients with comorbid cataract and primary open-angle glaucoma (POAG), guidance is lacking as to whether cataract extraction and traditional filtering surgery should be performed as a staged or combined procedure. Achieving this guidance requires an evidence-based understanding of the...
Risk of intraocular haemorrhage with new oral anticoagulants
The authors conducted a study to assess the risk of intraocular haemorrhage with warfarin dabigatran, rivaroxaban, apixaban. All reported cases of intraocular haemorrhage (vitreous, choroidal, or retinal) with warfarin and new oral anticoagulants (NOACs) (including dabigatran, rivaroxaban, apixaban) from the...
Effect of pregnancy on myopia
The authors present a longitudinal study with a large sample size assessing the association between pregnancy and the onset or progression of myopia. The study participants included the SUN cohort which comprised of young adult female university graduates in Spain....
Trabeculectomy for normal tension glaucoma
This is a retrospective consecutive, non-comparative case series of 131 eyes of 98 patients undergoing trabeculectomy between 2007 and 2013 in a normal tension glaucoma (NTG) clinic. Assessment of the clinical outcomes include intraocular pressures (IOP) reduction, bleb formation, final...
OCT angiography and retinal vein occlusions
In this retrospective, observational case series, the authors set out to evaluate the morphology of the superficial and deep capillary plexa of eyes that suffered a retinal vein occlusion (RVO) on OCT angiography (OCTA) and compare the findings with fluorescein...
Does the length of the school day have a role in age of myopia onset?
The authors prospectively collected the refractive data of myopic adults attending recruiting dispensing optician or ophthalmologist sites. Participants were recruited consecutively, giving verbal informed consent. Sites included a mix of urban and rural areas across eight sites. The following data...
How much money is wasted on tests prior to cataract surgery? And why?
For routine cataract surgery, numerous studies have found that preoperative testing does not contribute usefully to safety or surgical success. Despite such guidelines, tests ordered for patients prior to phacoemulsification in the US remains high. To quantify the associated costs,...
