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Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

1 October 2016 | | Retina / Uvea / Vitreous | chemotherapy, intra-ocular tumour, retinal pigment epithelium, retinoblastoma, toxicity
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Intracameral bevacizumab as an adjunct to trabeculectomy

1 April 2014 | | Clinical Trial, Glaucoma, Wound healing
This is a 12-month, prospective, randomised, double-masked, placebo-controlled trial of patients who were not controlled medically with open angle glaucoma and scheduled for a primary trabeculectomy. Patients were recruited and randomised during the period between April 2009 and November 2010....

Unexpected diagnoses – stroke in children and homonymous hemianopia

1 February 2022 | | Ophthalmology, Neuro-Ophthalmology, Imaging
We present the case of a 12-year-old child presenting with a few days history of left-sided visual loss. Upon further investigation with magnetic resonance imaging (MRI) she was unexpectedly diagnosed with a right-sided chronic posterior cerebral arterial territory infarct, causing...

How good does my vision have to be to drive this thing? Visual standards for various occupations

2 August 2022 | | Ophthalmology, Optometry
We can all picture that moment in clinic: you are about to tell someone that they’re no longer legally able to drive, ready to deploy our ‘breaking bad news’ techniques. For some patients this may have been expected, or they...

Lateral tarsal strip with skin-muscle flap excision in entropion

1 June 2018 | | Oculoplastics, Orbit | Skin-muscle flap, entropion, lateral tarsal strip
This was a retrospective study looking at effectiveness of skin-muscle flap in conjunction with a lateral tarsal strip for the correction of involutional entropion. Lateral tarsal strip was combined with a subciliary incision from canthotomy to just lateral to lacrimal...

Intraoperative floppy iris syndrome and prevalence of intraoperative complications

1 October 2014 | | Cataract and Refractive
Alpha-blockers (particularly of the selective type) are known to be associated with intraoperative floppy iris (IFIS) and poor dilation, which can present in various severities during cataract surgery and need to be recognised in order to avoid intraoperative complications. Methods...

Silicone band loop myopexy in the treatment of myopic strabismus fixus

1 June 2015 | | Paediatric Ophthalmology / Strabismus | Muscles
This is a retrospective case series of chart review of patients who had silicone band loop myopexy between January 2008 to December 2012 for myopic strabismus fixus (MSF) at a tertiary eye centre in India. A minimum period of two...

Strange Sequelae Succeeding ‘Surfer’s Eye’

1 February 2014 |
Ophthalmologists in the UK are relatively infrequently faced with a patient requesting surgery for a pterygium. This condition is more common where ultraviolet exposure is greater, especially if coupled with activities associated with ocular surface irritation. For this reason, a...

Feb/Mar 2015 Quiz 1

1 February 2015 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
A 79-year-old male presented to the ophthalmic emergency department with a three week history of left eye pain. He also reported visual deterioration in the left eye over the same period. He suffered from degenerative myopia, with his spectacle prescription...

Vitreous loss fire drills – ophthalmic simulation improves trainee surgical competence and confidence with posterior capsule rupture scenarios

4 December 2023 | | Cataract and Refractive
Ophthalmic trainees have reported limited exposure and low confidence regarding the management of cataract complications such as posterior capsule rupture (PCR) / vitreous loss (VL). This report evaluates the impact of a simulation-based educational training event on these concerns. Introduction...

UKISOP 2023

2 November 2023
by Lorcan Butler, Optical Engagement Manager, thebraintumourcharity.org, UKISCRS is the UK & Ireland Society of Cataract & Refractive Surgeons who had their annual Conference in London with a two-day event at The Leonardo City Hotel. On the other hand, UKISOP...

My work experience with Great Ormond Street Hospital Young Persons’ Advisory Group for Research

11 June 2021 | | Ophthalmology, Paediatric Ophthalmology / Strabismus, Imaging, ONLINE EXCLUSIVE ARTICLES
For my school work experience I had the amazing opportunity to attend and work with the Great Ormond Street Hospital (GOSH) Young Persons’ Advisory Group for research (YPAG) (Figure 1). The GOSH YPAG is a group of young people aged...