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Early intraocular complications of aneurysmal subarachnoid haemorrhage

The aim of this study was to estimate the incidence of a whole spectrum of early intraocular complications in patients suffering from aneurysmal subarachnoid haemorrhage (SAH) and to identify factors that are potentially associated with these fundus findings. In total...

Gender and ethnicity related differences in optic nerve head

The authors investigated the effect of ethnicity and gender on optic nerve head morphology comparing Indian and Caucasian males and females. The optic nerve head was investigated using spectral-domain optic coherence tomography (SD-OCT). Results showed that disc and rim areas...

Role of fundus autofluorescence patterns and baseline atrophy area on geographic atrophy progression

Central geographic atrophy (GA) is one of the morphological sub types of late-stage macular degeneration. The natural course of the disease is characterised by expanding areas of macular atrophy, which cause absolute scotoma. Fundus autofluorescence (FAF) is derived from lipofuscin...

Reported cases of hemifield slide phenomenon

This article reports three cases of hemifield slide, a phenomenon whereby there is an inability to stabilise and fuse visual hemifields. It occurs with heteronymous visual field loss and is thought to result from the loss of corresponding retinal points....

Vital dyes in ophthalmology

This comprehensive review gives an excellent summary of the uses and properties of the different dyes available to aid better visualisation and diagnoses in ophthalmology. The authors clearly display the pharmacological properties, molecular details, osmolarity and indications in clinical ophthalmology...

Congenital aniridia clinical features

In this study the authors investigated the various ocular and systemic features associated with congenital aniridia in Indian eyes (262 eyes of 131 patients). The median age at time of first hospital visit was eight years (one day to 73...

MicroRNA mediate retinoblastoma signal transduction

MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...

The prevalence of macular cysts in patients with clinical cone-rod dystrophy determined by spectral domain optical coherence tomography

Cone-rod dystrophy is a progressive photoreceptor disorder which has multiple inheritance patterns. It is rare, with a prevalence of 1 in 40,000. Macular cysts are well recognised in other photoreceptor conditions such as retinitis pigments and choroideraemia, while they are...

Persistent subretinal fluid (PSFF) in pneumatic retinopexy (PNR) versus pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD): posthoc analysis of the PIVOT randomised trial

This is a posthoc study of the PIVOT randomised trial over a 12 month period, to evaluate the functional outcomes of the incidence of PSF in PnR versus PPV following RRD surgery. One hundred and fifty-eight patients were recruited and...

Ocular characteristics in Marfan syndrome

Marfan syndrome (MFS) is a genetic disorder with clinical manifestations associated with cardiovascular, ocular and skeletal organ systems. Typical signs are descending aortic root aneurysms, ectopia lentis, tall stature and scoliosis. This observational study looked at the ocular characteristics, visual...

Microperimetry of subretinal drusenoid deposits

Subretinal drusenoid deposits (SDD), originally termed ‘reticular pseudo-drusen’, have recently been identified by histology and optical coherence tomography (OCT) as aggregations located in the subretinal rather than the sub retinal pigment epithelium (RPE) space. These deposits affect the amount of...