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1748 results found

The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy

The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...

Medical malpractice in uveitis: a review of clinical entities and outcomes

This paper presents a retrospective review of malpractice verdicts, rulings and settlements in the United States. Twenty-five cases of uveitis-related litigation spanning 1971-2014 were identified from the database representing 2.3% of all cases. Forty-eight percent of the cases were infectious....

Uveitic glaucoma

The purpose of this retrospective study from two tertiary Institutions in Israel over a period of 13 years, is to present the long-term outcomes of uveitic glaucoma and to identify risk factors for progression. The study included 34 patients (53...

Risk with density of suppression

The authors wished to determine the current practice of assessing and interpreting the density of suppression with the Sbisa / Bagolini filter bar in the management of amblyopia in the UK and to estimate the incidence of intractable diplopia following...

Clinical outcomes of AMT in acute ocular chemical injury

This is a retrospective study of patients from two units in Germany and UK between 1998 and 2008. The ocular chemical burns were classified by Roper-Hall and Dua classifications. A total of 72 eyes of 54 patients aged 37.3 years...

Ptosis frontalis sling surgery

In this retrospective study the authors investigated the functional and cosmetic outcomes of the modified frontalis sling procedure using silicone rods. The study included 17 patients (26 lids) and nine had bilateral surgery. An excellent outcome was defined as alignment...

Does Acanthamoeba need bacteria to cause keratitis?

An animal study was carried out on 36 rabbits, whose corneas were inoculated with either Acanthamoeba castellanii alone, Pseudomonas aeruginosa alone or both pathogens together after a period of short (two hours) or long (six hours) co-incubation. The clinical severity...

Aquaporin-4 antibody testing in isolate optic neuritis

The authors present a retrospective case review of first presentation isolated cases of optic neuritis tested for aquaporin-4 antibody across two centres over a nine-year period. Exclusion criteria included known diagnosis or other manifestations of neuromyelitis optica spectrum disorder. Two...

Conjunctival mapping biopsies in sebaceous carcinoma

This is a retrospective review of conjunctival mapping biopsies in patients with periocular sebaceous cell carcinoma. The authors reviewed the biopsy technique and outcomes of 45 patients who had mapping biopsies performed over a 25-year period. A total of 429...

Prediction of recurrence in exotropia

This study compares the long-term motor and sensory outcomes between constant and intermittent exotropia in infancy and investigated whether constancy can be used as a reliable factor for predicting surgical outcomes. Sixty-seven patients were reviewed – 37 constant and 30...

Nystagmus surgery

This study used a questionnaire-based assessment of the qualitative experience of adults and parents of children who had 4-muscle tenotomy surgery for nystagmus. Pre and postoperative video recordings and visual acuity measurements were used to objectively assess the physical effect...

Conventional vs. accelerated cross-linking

The Dresden protocol of 3mW/cm2 irradiance for 30 minutes has been extensively studied and has shown advantageous clinical and topographical results. However, this protocol is time-consuming and therefore accelerated CXL using higher irradiance to shorten treatment duration has emerged. The...