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Community Eyecare Services in Northern Ireland: putting the patient at the centre, improving outcomes and maximising system resource

The UK has four healthcare systems; Northern Ireland, Scotland and Wales each has autonomous legislature that develops health policy, while the UK government directly runs England’s NHS. Like the other nations, Northern Ireland is continually challenged to meet the needs...

Is lens constant optimisation for IOLMaster indispensable in order to achieve a good refractive outcome?

A study of refractive outcomes following cataract surgery was carried out with the aim of comparing the postoperative refractive outcomes against Royal College of Ophthalmologists standards and to determine the extent of association between accuracy of intraocular lens (IOL) power...

Systemic pharmacology of intravitreal anti-VEGF

This study aimed to evaluate and compare serum drug concentrations and plasma free-VEGF concentrations in patients with AMD, DME, or RVO receiving intravitreal injections of aflibercept, bevacizumab or ranibizumab. This prospective study enrolled patients from several offices of a single...

DSEK – five year results

This UK based study examined long-term descemet stripping endothelial keratoplasty (DSEK) results, looking at graft survival and endothelial cell losses. Data on 210 grafts were included in analysis. Most frequent indication for DSEK was Fuch’s endothelial dystrophy (81.4%) and 46.3%...

How to get the most out of your medical school ophthalmology placement

Ophthalmology has become a very popular speciality, generating a vast interest amongst medical students with competition for training posts increasing yearly. Yet it is often difficult to get adequate exposure to the speciality prior to applications, with very limited time...

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

Protecting retinal ganglion cells

Glaucoma is considered to be a heterogeneous group of conditions giving retinal ganglion cells (RGC) damage. Lowering intraocular pressure (IOP) reduces the risk of progressive RGC loss in glaucoma. Regeneration of the optic nerve has been shown to restore some...

Large collar diameter Jones tubes

This is the first report of the success rates of frosted Jones tubes with larger diameter, 4.5 or 5mm collars. This is a retrospective review of 29 eyes of 25 patients who underwent insertion of a large diameter collar frosted...

Natural history of idiopathic intracranial hypertension depending on incidental or symptomatic presentation

The authors present a large retrospective review cohort of consecutive patients diagnosed or presumed idiopathic intracranial hypertension (IIH) over a three-year period at a single tertiary centre. Patients on medication with a known aetiology for IIH were excluded. The cohort...

NICE drugs: an update on what’s good to go

Treatment options recommended by the National Institute for Health and Care Excellence (NICE) must be readily available for use in the NHS of England and Wales. This article provides an overview of recent guidance from NICE and summary advice issued...

D-EYE device versus direct ophthalmoscope

D-EYE digital ophthalmoscope is a fundus camera device that attaches to a smartphone and is used in conjunction with a HIPAA-compliant app. The authors conducted a study in which 25 medical students examined the fundi of two undilated patients with...

Cost-effectiveness framework discussion for vision screening

The authors present a discussion paper on hypothetical, but representative, examples of post-referral costs that may result from different screening options up to the point of discharge from specific services. Data was taken from a recent (2019) systematic review (with...