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Eye scans detect signs of Parkinson’s disease up to seven years before diagnosis
A team led by Siegfried Wagner and Pearse Keane of Moorfields Eye Hospital and UCL Institute of Ophthalmology (and spanning UCL institutions) has identified markers that indicate the presence of Parkinson’s disease in patients on average seven years before clinical presentation.Randomisation, confounding & observational methods in ophthalmic epidemiology
Randomisation and confounding Understanding the relationship between an exposure and an outcome of interest is the central challenge in ophthalmic epidemiology. The exposure may be aetiological, taking the form of a putative risk biological factor, or therapeutic, in the form...
Effects of topical anaesthetic on intraocular pressure
This prospective interventional study assessed the effects of repeated intraocular pressure (IOP) using Goldmann applanation tonometry and applanation resonance tonometry in six volunteers. Previous literature supports IOP reduction using repeated applanation tonometry. Repeated IOP measures were taken alternately on 12...“Herr Doktor, I can’t see but I am driving”
This 56-year-old lady was quite puzzling. With her own glasses and the pinhole she merely managed to see the 1.3 and 1.0 logMAR lines with her right and left eye, respectively (I am currently working in Germany again, so goodbye...The results of the last survey Oct 2019
Another fascinating response which once more highlights the massive variation in practice. I completely acknowledge that ophthalmology is an art as well as a science and therefore there will be variances in practice and there will not be one ‘right’...
Laser pointer maculopathy
The objective of this study was to describe the potential clinical presentations of retinal pathology resulting from exposure to laser pointers. The study included eight eyes of seven patients. Mean age was 18.7 years (12-36). Most were accidental self-inflicted while...
Using MRI to assess normal variation in optic chiasm anatomy
The authors present an MRI study including 61 MRI scans using a 1.5 T with slice thickness of 1 or 5mm and the sequence showing the highest resolution of the chiasm. A predetermined set of measurements were taken in a...
Single muscle surgery for hypertropia
The authors undertook partial tenotomies combined with graded marginal recession of single vertical rectus muscles to treat small angle hypertropia in four adults with fusion potential. They report dose response, surgical technique and outcomes. Dose response closely matched the theoretical...The paediatric cataract: an overview of the embryology and pathophysiology
In the first of the two articles (see Part 2 here) on paediatric cataracts, Samuel Aryee reviews the aetiology of this condition. Cataracts arise from opacification of the natural transparent lens, which can cause partial or total blindness. Although the...The results of the last survey Dec23
*Please be aware that this data does not form part of a peer reviewed research study. The information therein should not be relied upon for clinical purposes but instead used as a guide for clinical practice and reflection. Hopefully by...An anterior segment lump: a diagnostic and treatment challenge
Case presentation A 50-year-old female presented to eye casualty with a lump on the left medial lower eyelid with associated redness and occasional bleeding. The lump was present for a few months with recent enlargement (Figure 1). Her past medical...
