You searched for "Gene therapy"
Neurofibromatosis with multiple bilateral choroidal nevi and literature review
14 November 2024
| Mehru-Nisah Hanif, Syed Raza Ali Zaidi, Nausheen Hayat
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EYE - Imaging, EYE - Oncology, EYE - Vitreo-Retinal
The aim is to present a case of neurofibromatosis type-1 (NF-1), also known as von Recklinghausen disease, who presented with bilateral multiple choroidal nodular nevi following chemotherapy and mastectomy for breast cancer. Neurofibromatosis type-1 presents as a wide range of...
The role of virtual Rb-NET Multidisciplinary Team meetings in the management of children with retinoblastoma in low- and middle-income countries
6 April 2021
| Ido Didi Fabian, Nick Astbury, Elizabeth Dennis Nkanga, Anne Ampaire Musika, Susanna Ajayi, Marcia Zondervan
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EYE - Pathology, EYE - Oncology, EYE - Orbit, EYE - General
A selection of participants in an MDT meeting with Uganda. In 2017 the LINKS Programme developed a new network of LINKS to support and coordinate action against retinoblastoma (Rb) in response to requests from low- and middle-income countries (LMICs), called...
Quality of life concerns after uveal melanoma diagnosis
The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...Quiz Oct/Nov 2024
History An 83-year-old female was previously treated by surgical excision and plaque brachytherapy for her left conjunctival lesion. She presented to her ophthalmologist with a recurrence some years later and underwent a lid sparing orbital exenteration, which was sent to...Establishing an intra-arterial chemotherapy service for children with retinoblastoma in Nigeria for the first time
3 April 2023
| Mattan Arazi, Oteri Okolo, Dupe Ademola-Popoola, Richard Bowman, Ido Didi Fabian, Covadonga Bascaran, Marcia Zondervan
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EYE - General
This is the first in a series of three articles (see Part 2 here) about strengthening eye health services in Nigeria through collaboration with the LINKS and Networks run at the International Centre for Eye Health, London School of Hygiene...
Saccades and contrast sensitivity in retinoblastoma survivors
3 April 2024
| Lauren R Hepworth
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Paediatric Ophthalmology / Strabismus
The authors report a cross-sectional study, which recruited children aged 5 to 18 years old who completed treatment completion for retinoblastoma more than six months ago. Exclusion criteria included bilateral enucleation and pre-existing conditions associated with cognitive impairment. A total...
My top five: Emerging alternatives to manage and treat nAMD
3 April 2024
| Nikhil Sharma, Paras Agarwal
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EYE - Vitreo-Retinal
Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...
My Top Five: Emerging alternatives to manage and treat nAMD
3 April 2024
| Nikhil Sharma, Paras Agarwal
|
EYE - General
Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...
Understanding vasoproliferative retinal tumours
Syed Irtiza Ali Shah explores this rare and unusual condition through a fascinating case presentation. Vasoproliferative tumours of the retina (VPTR) are a vascular mass with an associated exudative retinopathy alongside the presence of minimally dilated feeder vessels. This is...Treatment of diabetic macular oedema
1 June 2014
| Samantha S Mann
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EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is a common complication associated with diabetic retinopathy, and the most common cause of visual impairment in diabetes [1]. With predicted rising levels of diabetes (in England by 2025 the estimated population with diabetes will be...
Birdshot retinochoroiditis
Birdshot retinochoroiditis (BRC) is a chronic, sight-threatening uveitis, most commonly affecting caucasian individuals in their fourth to sixth decades [1]. The disease is associated with HLA-29 and is characterised by progressive inflammation at the level of retina and choroid, with...
Mimicked tumour seeding due to asteroid hyalosis
5 October 2020
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
A case report is presented of a patient with treated retinoblastoma (RB) who later developed asteroid hyalosis which mimicked tumour seeding. The case was a 37-year-old male with presenting symptoms of vitreous floaters. A unilateral RB was diagnosed at the...
