You searched for "embryology"
Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells
1 October 2016
| Bheemanagouda Patil
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EYE - Vitreo-Retinal
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...
Effect of anti-VEGF treatment on PED morphology
1 June 2015
| Jaya Myneni
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EYE - Vitreo-Retinal
This retrospective study of 30 eyes assessed the effect of anti-VEGF on morphology of pigment epithelial detachments (PED) secondary to age-related macular degeneration (AMD). Thirty eyes of 28 patients with PED were compared to 30 eyes of 30 patients with...
Macular slippage following macular hole surgery
1 April 2014
| Khadijah Basheer
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EYE - General
The treatment of macular holes now involves peeling the internal limiting membrane (ILM) as well as vitrectomy and gas tamponade. It has been noted in previous studies that following an ILM peel the morphology of the macula is different. Tadayoni...
Patients blinded by stem cells! How safe are they really?
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Patients blinded by stem cells! How safe are they really? Ever since the successful results following...Birmingham Neuro-Ophthalmology: The Birmingham Efferent Course
17 January 2025
Objective:The aim is to review the physiology and the pathology of eye movements. The course is aimed at ophthalmologists, neurologists and orthoptists of all grades. It will be of value to those preparing for exams or refreshing their neuro-ophthalmology knowledge....
Acetylcholine receptor antibodies in the diagnosis of ocular myasthenia gravis at the Manchester Royal Eye Hospital
3 August 2023
| Nouf Alnafisee, Joanna M Jefferis
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EYE - Neuro-ophthalmology
Myasthenia gravis (MG) is the commonest autoimmune condition to affect the neuromuscular junction. In the UK, its prevalence is 15 per 10,000 [1,2] and recent studies have shown that rates are steadily increasing [3,4]. Aims of this audit The aim...
The clues of the eye – what is medical ophthalmology?
1 February 2022
| Nima John Ghadiri
The author looks at the increasingly significant role of medical ophthalmologists and the importance of integrative healthcare. The eye is a remarkable organ, and for decades we have been discovering intimations of pathology existing elsewhere in the body [1] simply...
A Multidisciplinary Approach to Neovascular Glaucoma in a Patient with Waldenström’s macroglobulinemia
1 December 2013
| Inderpaul S Sian, Karl Whittaker
An 84-year-old Caucasian male attended eye casualty with a four month history of reduced vision, a dull ache and photophobia in both eyes. He had also reported dizziness, weakness and intermittent epistaxis in the nine months prior to presentation. There...
The power of the full blood count
Vishal Shah walks us through his thought process whilst highlighting the importance of routine investigations when dealing with unusual retinovascular presentations. Retinal changes can arise in anaemia, leukaemia, lymphoma, myeloproliferative and myelodysplastic syndrome. They are often the first manifestation of...Coeliac disease and anterior scleritis
1 February 2014
| Saruban Pasu
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Paediatric Ophthalmology / Strabismus
The authors present an interesting case report of recurrent anterior scleritis. Circulating IgA and IgG auto-antibodies directed against tissue transglutaminase, endomisium and gliadin are frequently elevated in patients with coeliac disease. The classic symptoms remain chronic diarrhoea, malabsorption syndromes and...
Corneal Transplantation
1 February 2017
| Shirley Hancock
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EYE - Cornea
This relatively small book provides a thorough overview of the history of corneal transplantation, an update on the anatomy and physiology of the cornea with particular reference to the components essential to keratoplasty procedures, also graft preparation and storage. There...