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Comparison of bupivacaine injection vs. mini-tenotomy for small angle deviations

Bupivacaine hydrochloride is an aminoacyltype local anaesthetic. Injection into extraocular muscles elicits a myotoxic response destroying striated muscle fibres but sparing satellite cells, nerves and vessels. Preserved satellite cells proliferate to form new muscle fibres, causing muscle hypertrophy and greater...

What's trending Oct/Nov 2020

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #oldEnglish #herbalremedies Researchers from the University of Warwick, investigating natural remedies to treat bacterial infections, have discovered a potential new treatment....

An unusual case of partial oculomotor nerve palsy

The authors present an unusual case of intra-axial oculomotor nerve involvement due to midbrain infarction. The 65-year-old male patient presented with unilateral complete blepharoptosis and slight limitation of upgaze. Neurological examination revealed a complete ptosis of the left eyelid, slight...

Evisceration in India: demographic and clinical trends from a large multicentre cohort study

In this multicentre cohort study, the authors investigated a total of 2071 patients who underwent evisceration with primary implant placement over a six-year period at four tertiary eyecare centres in India. Out of 1,345,480 new ophthalmic presentations during the study...

Ozurdex use in noninfectious uveitis

Burkholder et al. reported the practice patterns of 45 respondents of approximately 176 surveyed members of the American Uveitis Society regarding the use of the Ozurdex implant. Most respondents performed the injection in either a procedure (41.0%) or clinic (23.1%)...

Review of paediatric infectious endophthalmitis

This paper presents a review on paediatric infectious endophthalmitis and considers aetiology, prognosis and management. Classification included exogenous and endogenous. Diagnosis was based on presenting history, signs and symptoms, cultures and imaging. Exogenous cases included postoperative endophthalmitis (strabismus surgery, glaucoma...

How do you solve the problem of trachoma in Ethiopia?

Background Trachoma is one of the oldest diseases known to humankind and the leading infectious cause of blindness worldwide. Spread by the bacterium chlamydia trachomatis, it is transmitted through contact with the eyes, eyelids and nose of those infected. The...

G-CSF intravitreal injections for NAION: a pilot study

In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...

RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions

This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...

Triamcinolone (TA) deposits following subcutaneous injection to treat chalazion

Chalazia are chronic lipogranulomatous inflammations of the eyelid secondary to a blocked meibomian gland. Whilst most resolve spontaneously, certain chalazia warrant treatment. Options include incision and curettage (I&C), lesion excision, intralesional steroid injections, and botox injections [1]. I&C is usually...

Quiz Oct/Nov 2022

History An Afro-Caribbean woman, aged 30, with “scleral tattooing” for cosmetic reasons (subconjunctival dye injection), presented with bilateral upper and lower eyelid oedema for one week, and she also had restricted eye movement and blurry vision in her right eye....

Cytomegalovirus retinitis post intravitreal triamcinolone in an immunocompetent patient with juvenile glaucoma

Figure 1: Fundus photograph shows active CMV retinitis four weeks after IVTA in the right eye. Figure 2: Fundus photograph of the left eye with no CMV retinitis; atrophic disc as a result of juvenile glaucoma. Case report A 29-year-old...