You searched for "ocular"
Intravitreal aflibercept for diabetic macular oedema
The VISTA and VIVID randomised phase 3 trial were designed to compare the efficacy and safety of intravitreal aflibercept injections versus laser photocoagulation for diabetic macular oedema (DMO). A total of 872 patients with centrally involving DMO were recruited, and...
The rarebit vision test for macular conditions
Rarebit testing is used to measure low degrees of neuro-visual damage and is available for free on the internet. It consists of a fixed bright light dot presented on a black background. During testing it is presented briefly at different...
Is an increased homocysteine level associated with greater risk of AMD?
Basic research studies have implicated homocysteine in causing vascular endothelial dysfunction and inflammation, and this has been borne out in large observational studies which suggested that elevated homocysteine is associated with increased risk of cardiovascular disease. In order to determine...
VEGF and axial length (RVU)
The authors of this paper set out to examine whether the concentrations of VEGF in the vitreous were associated with refractive error and axial length in eyes without retinal disease, except of macular holes or epiretinal membranes. A vitreous sample...
Choroidal and macular thickness in nonarteritic anterior ischaemic optic neuropathy
This study evaluates the choroidal and macular thickness in patients with chronic nonarteritic anterior ischaemic optic neuropathy (NA-AION). Two groups of subjects were compared, group one included 20 eyes with chronic NA-AION and group two, 31 healthy control eyes. The...
Detection of antiranibizumab antibodies in exudative AMD
In this study the authors aimed to detect immune response to ranibizumab treatment in wet age-related macular degeneration (AMD). An ELISA was employed to quantify the anti-ranibizumab titre which was compared against the control anti-abciximab titre. Titres of anti-ranibizumab antibodies...
Visual acuity after cataract surgery in AMD patients
The data from this study are obtained from the Age-Related Eye Disease Study (AREDS) 2 and analysed to evaluate if cataract surgery benefits patients with concurrent age-related macular degeneration (AMD). The AREDS 2 was a five year, prospective, multi-centre randomised...
Reduced blood flow and age-related macular degeneration
This was a prospective cross-sectional study assessing changes in blood flow velocity in patients with age-related macular degeneration (AMD) using a retinal function imager. Sixty eyes with wet AMD were compared to 53 control eyes and the average blood flow...
Avastin vs. Volon A for diabetic macular oedema
This prospective randomised interventional clinical trial compared 30 diabetic patients with macular oedema treated with either intravitreal injections of bevacizumab (Avastin) or triamcinolone (Volon A). One group initially received three injections of 2.5 mg Avastin in monthly intervals whilst the...
Oral proton pump inhibitors in macular degeneration patients
The authors report five patients with advanced wet macular degeneration and poor vision with onset or enhancement of visual hallucinations with the use of proton pump inhibitors for heartburn management. The hallucinations were reversible with discontinuation of medication. The authors...
