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Age and gender impacts effectiveness of new gene therapy treatments for eye diseases, new study finds

14 February 2025 | research, genetics, gene therapy, pathology, education, Adeno-Associated Virus, inflammation
Older women could be vulnerable to harmful inflammation from new gene therapies to treat incurable eye diseases, new research has found. The University of Bristol-led study, published in Molecular Therapy, reveal how age and gender affects inflammation caused by gene...

Aug/Sep 2014 Quiz 1

1 August 2014 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 50-year-old female with a history of smoking, weight loss and cough presents to the ophthalmology clinic with a distorted pupil. Examination reveals a mass on the surface and within the iris (see Figure 1). The ophthalmologists decide to...

Quiz Oct/Nov 2022

3 October 2022 | | EYE - General
History An Afro-Caribbean woman, aged 30, with “scleral tattooing” for cosmetic reasons (subconjunctival dye injection), presented with bilateral upper and lower eyelid oedema for one week, and she also had restricted eye movement and blurry vision in her right eye....

Over one million estimated to have glaucoma in UK

5 February 2026 | glaucoma, research, patient stories
Over one million people are estimated to currently have glaucoma in the UK, a figure projected to reach more than 1.6 million by 2060, according to a study led by Moorfields and UCL researchers. The new figures, published in the...

What's trending Feb/Mar 2019

1 February 2019 | | EYE - Cataract, EYE - Refractive, EYE - Cornea, EYE - Glaucoma, EYE - General
A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #smartcaptionglasses #Epson #livetheatre #deaf Here is some good news for the New Year. Epson, a Japanese technology firm, has developed...

Unilateral central scotoma following dengue fever

12 October 2023 | | EYE - Neuro-ophthalmology
Case report A 16-year-old Caucasian male was referred to the eye casualty at Nottingham University Hospitals NHS Trust by the infectious diseases unit in September 2013. He gave a history of photophobia, pain on eye movements and central blurred vision...

Pituitary tumours: why are they so often missed?

1 April 2017 | | EYE - Neuro-ophthalmology
Part 1: Introduction, historical background and Edinburgh connections (see also Part 2 and Part 3) Is there any ophthalmologist who has not missed a pituitary tumour? Hopefully this article will help those currently in practice to avoid such an embarrassment,...

A pituitary tumour from 1927

1 April 2019 | | EYE - Neuro-ophthalmology, EYE - General
The author shares a clinical case from Edinburgh Royal Infirmary’s archives. It is not often in the course of a clinical career that one gets the opportunity to review a patient who had been treated by a pioneer neurosurgeon some...

Measuring patient-reported outcomes after refractive surgery to assess patient satisfaction

1 June 2019 | | EYE - Cataract, EYE - Refractive, EYE - General
Patient-reported outcomes enable surgeons to evaluate patients’ symptoms and satisfaction after laser vision correction. The great majority of patients are pleased with their outcomes from laser vision correction, whether it is with photorefractive keratectomy, laser in-situ keratomileusis (LASIK), or small...

Acute management of retrobulbar haemorrhage

1 February 2022 | | EYE - Orbit, EYE - Oculoplastic
The authors discuss the importance of rapid diagnosis and correct management of acute RBH presentation to avoid the risk of permanent blindness. Retrobulbar haemorrhage (RBH) is an ocular emergency that occurs due to arterial bleeding in the orbital cavity behind...

Does vitrectomy increase the risk of glaucoma? A retrospective review from a UK hospital

5 April 2022 | | EYE - Glaucoma, EYE - Vitreo-Retinal, EYE - General
The authors investigate what proportion of patients undergoing pars plana vitrectomy subsequently developed ocular hypertension or a diagnosis of glaucoma. A systematic review carried out in 2017 including seven studies found that there is evidence that pars plana vitrectomy (PPV)...

Insects, swelling and sight loss: a case of orbital inflammatory syndrome

1 June 2022 | | EYE - General
Despite being the most common cause of painful orbital mass in adults and the third most common orbital disease, orbital inflammatory syndrome still proves to be a difficult ocular condition to diagnose, treat, and manage. A 41-year-old lady presented to...