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Review of non-arteritic anterior ischaemic optic neuropathy

1 October 2016 | | Neuro-Ophthalmology | Neuroprotection, optic nerve ischemia, optic nerve vasculature, primate models, rodent models
This article reviews the risk factors, clinical presentation and therapies that have been investigated for non-arteritic anterior ischaemic optic neuropathy (NAAION). Additionally, it provides an update from recent rodent and primate models, offering a new insight into the pathophysiology of...

Intravitreal ranibizumab for the treatment of myopic CNV

1 April 2015 | | Retina / Uvea / Vitreous
The authors conducted a prospective study. Sixty-four patients (65 eyes) attended the 12-month follow-up examination. The mean patient age was 47.8 years. Fifty-five patients (86.0%) were females. All patients had pathologic myopia (a spherical equivalent of more than − 6.0...

My top five: Trinkets of fact or fiction

3 June 2024 | | Ophthalmology
Trinkets of adult wisdom are often delivered to children alongside warnings of catastrophic outcomes. In this article we present five ‘facts’ about eye health and vision and ask the question: to what extent are these ideas backed up by literature?...

Stem cell therapy for Parkinson’s disease: researching for an 
effective cure

1 December 2015 | | Neuro-Ophthalmology
Neurodegenerative diseases are characterised by the chronic and progressive loss of neurons, which in turn results in loss of cognitive and physical functions. The World Health Organization has estimated that the disability-adjusted life years lost from neurological disease was about...

The structure function relationship in glaucoma

1 April 2017 | | Glaucoma
Chronic open angle glaucoma (COAG) is the second most common cause of blindness worldwide. It is diagnosed on the basis of three clinical signs, raised intraocular pressure (IOP), visual field (VF) defects and structural changes to the optic nerve head...

Understanding the inequalities of ophthalmic care for Indigenous people in a first world country

6 November 2023 | | Ocular Pathology and Oncology
Aboriginal Australians have faced numerous challenges over the past centuries. Here in this article, Edward Saxton highlights why there are inequalities of ophthalmic care in Australia and why this has led to increased levels of blindness in Aboriginal people relative...

Quiz Oct/Nov 2022

3 October 2022 | | Ophthalmology
History An Afro-Caribbean woman, aged 30, with “scleral tattooing” for cosmetic reasons (subconjunctival dye injection), presented with bilateral upper and lower eyelid oedema for one week, and she also had restricted eye movement and blurry vision in her right eye....

Hydroxychloroquine toxicity

1 August 2017 | Ophthalmology, Retina / Uvea / Vitreous
Being the subject of litigation is stressful and upsetting. Having to look back over your previous decisions and justify the care you delivered in good faith can be difficult. Sadly, we all live with the Sword of Damocles above us...

Retinal sequelae of high voltage electric current injury

5 June 2023 | | Retina / Uvea / Vitreous
Introduction High-voltage electrical currents may result in significant ocular complications, ranging from mild cataracts to vision-threatening retinal and optic nerve problems [1]. The severity of damage depends on various factors, including intensity and type of current, duration of exposure, entry...

Periorbital and subconjunctival emphysema - a sign of orbital rim fracture

3 February 2023 | | Ophthalmology
Background Orbital emphysema is a condition where air is present in orbit or periorbital tissues [1]. It is most commonly caused by trauma leading to orbit fracture, where air from paranasal sinuses is allowed to enter the orbit. The most...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

4 August 2021 | | Ophthalmology, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Amnion-assisted conjunctival epithelial redirection (ACER): Enhancing stem cell transplantation treatment of total limbal stem cell deficiency

1 April 2019 | | Ophthalmology, Cornea / External Eye Disease
An exploration of Professor Harminder Dua’s recent work using a technique called amnion-assisted conjunctival epithelial redirection (ACER) to aid the success of conjunctival-limbal grafting procedures. ACER provides a refined way to use amniotic membrane (amnion), such as Omnigen® (NuVision® Biotherapies,...