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Developing community eye care: the evolution of Wales’ eye care services
In the third in our series about community eye care in the home nations, David O’Sullivan explains how Wales has developed its community eye care services. Since the devolution of healthcare to Wales on 1 July 1999 [1], significant changes...Designing ophthalmology services Part 2: How do we address the queues for a clinic?
The first of this three-part series showed how systems engineering can be used to correctly diagnose and address the causes of delays in a clinic. This second article describes how to design a more productive system that meets the new...
Leber’s hereditary optic neuropathy: from lab to clinic
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...Managing a patient with ptosis
A 50-year-old male patient is referred from the Accident & Emergency department with a history of ptosis. How will you manage this patient? Mr Bertie Fernando Clinical management Clinical management starts with a sound clinical history. Current history The history...Breakthroughs in the genetics of angle-closure glaucoma
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...A near miss
A 55-year-old gentleman presented with a ‘blurry patch’ to his left eye which he had noticed for the past two months. The visual acuity with correction was 6/5 in the right eye and 6/6 in the left eye on the...Optegra celebrates 15th anniversary and announces expansion plans
Specialist eye hospital Optegra marks its 15th anniversary this month, having opened its first UK hospital in Guildford in 2008.The fragile p-value
Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...
How long to wait to refract after instilling cyclo drops for children with brown irides?
This study aimed to assess the time needed for effective cycloplegia after instillation of 1% cyclopentolate drops in children with brown irides. The study recruited 161 consecutive patients aged three to 16 years. All had refraction on arrival, then instillation...
Visual outcomes after surgery for primary rhegmatogenous retinal detachment in era of microincision vitrectomy
This is a prospective, multicentre, nationwide study between 2016 and 2017, to investigate the preoperative ocular factors, surgical techniques (pars plana vitrectomy (PPV) or scleral buckling (SB), or combined procedures) for rhegmatogenous retinal detachment (RRD) and postoperative best corrected visual...
