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1763 results found

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

Evaluating ocular motor functions

Traditionally orthoptists are specialised in assessing ocular motor disorders. This article introduces the ocular motor score as a new clinical tool for screening and follow-up for children and young adults. The protocol consists of 15 tests such as stereoacuity, strabismus,...

Early postoperative angle for prediction of surgical success for exotropia

In this study, the authors assessed the relationship between the initial postoperative deviation and surgical outcomes in adult exotropia undergoing unilateral lateral rectus recession with medial rectus resection. The study included 93 patients (51 female); 26 with residual exo, 53...

Ametropic amblyopia and stereopsis

This study aimed to evaluate the correlations between ametropic amblyopia (hypermetropic – 110, myopic – 30, and astigmatic – 65) and stereopsis in 205 children – mean age of 5.2 years ±1.8. For near stereopsis, significant results were found for...

OCT choroidal signs for congenital retinal pigment epithelium hypertrophy

Congenital hypertrophy of the retinal pigment epithelium (CHRPE) on ocular coherence tomography (OCT) has the characteristic sign of RPE thickening and hyper reflectivity. However, the underlying choroid characteristics remain under researched. This retrospective study utilised data from an ophthalmic oncology...

A review of orbital plasmacytomas

This is a multicentre review of 30 patients with orbital plasmacytomas. There were equal numbers of males and females, and the average age at diagnosis was 57 years. All patients were either already diagnosed with systemic multiple myeloma or it...

Observership in Dar es Salaam

In this report, both authors present their personal experiences of an observership at the Comprehensive Community Based Rehabilitation in Tanzania (CCBRT) Hospital, a large regional teaching hospital located in Dar es Salaam, with a particular focus on resource management, attitudes...

Capacity-strengthening for diabetic retinopathy services in low- and middle-income countries

Introduction DR-NET eye health professionals in low- and middle-income countries (LMICs) have, since 2015, been able to access training in diabetic retinopathy (DR) grading provided by Gloucestershire Retinal Education Group (GREG). GREG, led by Professor Peter Scanlon and based at...

Management of squint with near-distance angle disparity

These are a group of strabismus disorders where the angle of misalignment is different between near and distance. The focus of this article will be on the patients where the angle for near exceeds the distance angle by more than...

The science of glaucoma management: highlights of the 2020 Moorfields International Glaucoma Symposium

Held earlier this year, the 12th annual Moorfields International Glaucoma Symposium provided a forum for advanced clinical and scientific exchange in glaucoma management. The authors describe the key presentation themes and debates, highlighting specific topics of interest to glaucoma specialists....

Jason Turnbull takes on epic challenge: climbing 24 Munros in 2024 to support Sight Scotland Veterans

Jason Turnbull has embarked on a remarkable journey to climb 24 Munros throughout 2024 to raise funds for Sight Scotland Veterans, a charity dedicated to supporting visually impaired veterans throughout Scotland.

SCONe Project seeks participants for patient and public involvement group to revolutionise AMD research

The SCONe project, run by optometrists, ophthalmologists, and researchers from the University of Edinburgh, and funded by Sight Scotland, is appealing for participants to take part in a Patient and Public Involvement (PPI) group focused on revolutionising the detection and management of Age-Related Macular Degeneration (AMD).