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Internal limiting membrane (ILM) peeling on blood flow in diabetic macula

This is a retrospective review of notes for diabetic patients with epiretinal membrane (ERM) who underwent surgery by the same surgeon. Nineteen had ERM peeling only, while the remaining 18 had both ERM and internal limiting membrane (ILM) peeling. The...

Inverted internal limiting membrane flap vs internal limiting membrane insertion technique for large macular holes

This meta-analysis aimed to compare and evaluate the morphological and functional outcomes between the inverted internal limiting membrane (ILM) flap and ILM insertion techniques in the treatment of large macular holes (MHs). The primary outcome measures were defined by the...

Clinical characteristics and outcomes of open globe injury

This retrospective cohort study examined consecutive open globe injuries at a tertiary referral centre over a three year period. The aim of the study was to detail the clinical characteristics of open globe injuries and to explore their association with...

Phaco-ECP vs. Phaco alone to treat glaucoma

This retrospective review compared combined phacoemulsification and endoscopic cyclophotocoagulation (phaco-ECP) to phaco alone in patients with mild to moderate glaucoma. Outcome measures included cumulative full and qualified success survival, postintervention IOP and ocular anti-hypertensive medication reduction. Full success was defined...

Intensive diabetes therapy and ocular surgery in type 1 diabetes

The Diabetes Control and Complications Trial (DCCT) ran between 1983 and 1993 and showed that intensive glycaemic control was beneficial in reducing diabetic retinopathy in type 1 patients. There was a 76% reduction in onset of retinopathy and a 52%...

Choroidal and RNFL thickness in patients with OSAS

In obstructive sleep apnoea syndrome (OSAS), hypoxia secondary to repetitive apnoeic episodes leads to blood pressure variations and haemodynamic changes. There is also intermittent activation of the sympathetic system when the patient is aroused from sleep during apnoeic episodes. OSAS...

Outcomes of ‘treat and extend’ for neovascular AMD

The authors report on 24-month outcomes of anti-vascular endothelial growth factor (anti-VEGF) therapy using a ‘treat and extend’ regime for treatment-naïve neovascular age-related macular degeneration (nAMD). Data for this study was collected from the Fight Retinal Blindness observational registry based...

Aqueous humour cytokine levels in PCV and nAMD

This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...

Comparison of ganglion cell thinning in glaucoma vs. macular hole repair

This prospective study compared the changes in the photopic negative response of the focal macular electroretinogram (fmERG) caused by retinal ganglion cell complex (GCC) thinning at the macula between patients with open angle glaucoma (OAG) and 12 months after successful...

Uveitis in HIV infected persons

Before the advent of highly active antiretroviral therapy (HAART), uveitis, in particular cytomegalovirus (CMV) retinitis, was the most common cause of visual loss in patients with AIDS. HAART has altered the cause of ocular disease in HIV infected individuals by...

Four year outcomes of macular degeneration treated with ranibizumab

The authors report on a retrospective study of neovascular age-related macular degeneration (AMD) patients treated with a variable ranibizumab dosing regimen over a period of four years (from January 2007 to December 2011). A total of 600 treatment naïve eyes...