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A prospective trial of adjuvant therapy for high-risk melanoma
Patients diagnosed with iris, ciliary body or choroidal melanoma of high-risk tumour cytogenetics (monosomy 3>/= 20% of cells), were treated with adjuvant low-dose dacarbacine (DTIC) and interferon –alpha-2b (IFNA-2b), following primary treatment (enucleation, brachytherapy or resection). DTIC was given intravenously...
Visual field progression after glaucoma drainage device implantation
This retrospective interventional case series assessed changes to visual fields after implantation of a glaucoma drainage device (Baerveldt, Ahmed or Molteno Devices) between 2010 and 2015. A total of 106 eyes from 96 patients were included in the final analysis...
Validity of coding in neuro-ophthalmology within large administrative datasets
A systematic review of validation studies of the International Classification of Disease (ICD) coding system, ICD-9 and ICD-10 is presented by the authors. Three searches were conducted based on three concepts, firstly health administration claims and ICD codes, secondly diagnostic...
Long-term follow-up of OPGs in neurofibromatosis type 1
This retrospective observational case series reports outcomes of children followed-up for at least 10 years with optic pathway glioma (OPGs) related to neurofibromatosis type 1 (NF1) between January 1985 and July 2007. They observed 45 children for a mean of...
Guideline considerations for management of paediatric traumatic cataract
This study aimed to develop guidelines for preoperative decision-making and perioperative management of paediatric traumatic cataract patients. A 24-question survey was designed to assess surgeon background, preoperative planning and testing, surgical timing, intraoperative techniques and postoperative management. Anonymous responses were...
Secondary glaucoma post paediatric cataract surgery
This retrospective observational consecutive case series assessed the incidence and risk factors associated with developing glaucoma after paediatric cataract surgery with primary intraocular lens (IOL) implantation. They reviewed 136 children (199 eyes) who underwent paediatric cataract surgery before the age...
LACTOSE control score for exotropia
The purpose of this study was to determine the extent of change in control over multiple measurements in a single clinic visit using the Look and Cover, then Ten seconds of Observation Scale for Exotropia (LACTOSE) scoring system in patients...
Amniotic membrane transplantation for SJS/TEN
This is a retrospective study of consecutive patients who underwent amniotic membrane transplantation (AMT) in the acute stage of Stevens-Johnson syndrome (SJS) / toxic epidermal necrolysis (TEN) from Toronto, Canada, between 2009 and 2018 and had more than three months...
Factors influencing the outcome of GT and TBT in PCG
This is a retrospective study between 2013 to 2016 of 452 eyes of patients </=12 years with primary congenital glaucoma (PCG), who underwent either goniotomy (GT) (median age: six months, 120 eyes) or trabeculotomy (TBT) (median age: 5.2 months, 332...
Divergence insufficiency esotropia is increasingly more common and new theory of aetiology
The authors present a retrospective case review of acquired esotropia. An internal database was reviewed for cases of esotropia and divergence insufficiency between 1978 and 2018 and seen by a single ophthalmologist. Patients with initial presentation of esotropia onset after...
Ocular adnexal mantle cell lymphoma
In this study the authors compare primary ocular adnexal (OA) mantle cell lymphoma (MCL) with initially systemic MCL occurring over a 30-year period. MCL is a rare form of lymphoma accounting for 5-11% of OA lymphomas and therefore knowledge of...
