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1885 results found

Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Inverted internal limiting membrane flap vs internal limiting membrane insertion technique for large macular holes

This meta-analysis aimed to compare and evaluate the morphological and functional outcomes between the inverted internal limiting membrane (ILM) flap and ILM insertion techniques in the treatment of large macular holes (MHs). The primary outcome measures were defined by the...

Choroidal and RNFL thickness in patients with OSAS

In obstructive sleep apnoea syndrome (OSAS), hypoxia secondary to repetitive apnoeic episodes leads to blood pressure variations and haemodynamic changes. There is also intermittent activation of the sympathetic system when the patient is aroused from sleep during apnoeic episodes. OSAS...

Macular thickness and visual fields

The authors describe a comparison of spectral domain OCT with Humphrey visual fields (HVF) mean deviation (MD) and pattern standard deviation (PSD), examining the retinal thickness of the macula and circumpapillary retinal nerve fibre layer (RNFL) defects. Seventy-three subjects who...

Disc margin delineation using spectral domain OCT

Observing progressive anatomical changes of the optic nerve head is essential in the detection of progression in glaucoma. Imaging devices continue to evolve and are useful in detecting change in established glaucoma, although probably less useful in an initial diagnosis....

Comparison of structural and functional features in primary angle closure and open-angle glaucoma

In this large cross-sectional study, differences in structural and functional damage were assessed among patients with primary open-angle glaucoma (POAG) and primary angle closure glaucoma (PACG) with optical coherence tomography and reliable visual field testing. Two-hundred and eighty-three patients with...

Commonwealth nations join forces to prevent blindness from diabetes

More than 70 representatives from 10 Commonwealth countries (in the African, Caribbean and Pacific regions) and Indonesia gathered at a five-day workshop in November 2014 to establish district or national plans to reduce blindness from diabetic retinopathy (DR). The event...

NYU Langone Health performs world’s first whole-eye & partial-face transplant

Landmark whole-eye transplant is a major paradigm shift for potential vision therapies.

Zeiss Forum

The tech column this issue reports on the features and experience of using the Zeiss Forum software. I have overseen the installation, troubleshooting, training and use of the software over the last two years. As both a consultant specialising in...

Typical or surprisingly uncharacteristic presentations of neuro-ophthalmic emergencies

Irrespective of geographical location or patient cohort, emergency departments are high risk locations capable of inspiring extreme anxiety and dread in patients and doctors alike. The stress multiplies when a walk-in or referred case is suspected of underlying neurological pathology....

Blind veterans continue hillwalking passion thanks to power of VR

Imagine being a keen hillwalker who loves the outdoors but then being unable to enjoy it because of sight loss. Fortunately, many veterans of the Armed Forces who have visual impairment can climb their favourite mountains again, thanks to Sight Scotland Veterans.

90% of NHS trusts now have electronic patient records

The NHS has met the government’s target for 90% of trusts adopting electronic patient records (EPR) in hospitals ahead of schedule.