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Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...Discussing treatment modalities for bilateral wet AMD
A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....
The Retina Illustrated
I’ve always liked googling authors of the textbooks we get sent rather than relying on the very obviously bias blurb about them presented in the book. When I got Retina Illustrated I have to admit I was pretty excited to...
Retinal pigment epithelium tears
In this paper the authors review the current knowledge of retinal pigment epithelium (RPE) tears. Although rare these can cause loss of visual acuity. They can occur spontaneously in pigment epithelial detachment (PED) due to occult choroidal neovascularisation (CNV), retinal...
A standardised strategy for uveitis etiological diagnosis
This was a prospective, non-inferiority, multicentre randomised control trial, which aimed to assess the effectiveness of a standardised approach in the etiological diagnosis of uveitis versus an open strategy, where clinicians could perform any test. The authors developed their standardised...An unusual case of acute retinal necrosis
Case report A 40-year-old Caucasian male presented with a four-day history of redness and progressive painless reduction of vision in the left eye. His visual acuities were 6/4 in the right and 6/36 in the left. The left eye showed...
Handbook of Retinal OCT
This is not a large colour atlas for optical coherence tomography (OCT) with comprehensive reference lists offering an in-depth description of this popular technology, but an up-to-date pocket or handbag-sized, soft-backed textbook that is likely to become a well-thumbed primer...
Optical Coherence Tomography: A Clinical and Technical Update
This book is a comprehensive review of the clinical and scientific aspects of optical coherence tomography (OCT). The 255 pages are divided into 11 chapters, each written by a different group of authors. Part I provides viewpoints on the clinical...Life in the eye department
The crowd is gathering at the watering hole in the Serengeti that is Friday teaching at the Major Teaching Hospital. Would there be enough different species of consultant present or would there be insufficient numbers? If a critical mass of...
Using video-oculography to record monocular eye movements
The aim of this study was to examine the characteristics of monocular eye movements recorded using video-oculography (VOG). VOG monocular recording has become increasingly popular in comparison to electro-oculographic binocular recording, due to its simple technique. The authors evaluated the...
