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Macular atrophy with aflibercept

The authors of this paper set out to investigate the prevalence of macular atrophy in treatment-naive patients with neovascular AMD undergoing aflibercept monotherapy (three monthly loading injections followed by subsequent treatment every two months). Case notes over a three year...

Natural regression of brow heaviness in thyroid eye disease

This is a retrospective review of the change over time in the sub-brow fat volume in 104 patients with thyroid eye disease. Standardised photographs taken at diagnosis were compared with those taken after an average period of 10 years (+/-...

Choroidal vascularity in NAION

The authors present a cross-sectional, non-interventional study of healthy volunteers and those with non-arteritic anterior ischaemic optic neuropathy (NAION) recruited over a six-month period at a single site. NAION is the most common cause of acute optic neuropathy over the...

Two-year results of a T&E aflibercept regime in caucasian PNV

This a retrospective study examining two-year outcomes of patients with pachychoroid neovasculopathy (PNV) treated with a treat and extend (T&E) regimen of intravitreal aflibercept. The mean age was 63.84 ± 7.92 years with nine males (35%) and 17 females (65%)....

Features of AMD treatment non-responders

This is a retrospective consecutive case series of 365 eyes with age-related macular degeneration (AMD) who had three monthly intravitreal aflibercept treatments for at least 12 months. Responders were defined as complete resolution of exudation, intraretinal oedema, subretinal fluid, pigment...

Treat and extend for PCV

This South Korean study investigated the efficacy of a treat and extend regimen (TER) using ranibizumab to treat polypoidal choroidal vasculopathy (PCV). Twenty-nine eyes were included in this retrospective case note review. Of these, five eyes had been treated with...

Fluorescein angiography and OCT in myopic CNV

Fluorescein angiography (FA) and spectral-domain optical coherence tomography (OCT) are the most common examinations used in the management of anti-VEGF therapy in choroidal neovascularisation (CNV). In comparison to FA, OCT provides a noninvasive evaluation of the macula. Myopic CNV are...

B-scan ultrasonography

B-scan ultrasonography is commonly employed for the diagnosis and follow-up of ocular trauma. This retrospective study looked at the accuracy and predictive ability of B-scan ultrasonography following open globe repair. Of the 965 patients identified with open globe injuries at...

Recession and resection surgery in TED

The aim was to investigate changes in ocular ductions in thyroid eye disease (TED) patients undergoing recession in comparison to recession / resection surgery. This was a retrospective study of 119 patients with inclusion of 102 eyes in final analysis....

Vertical angle surgical outcomes

The surgical results of all patients undergoing isolated adjustable suture vertical squint surgery for thyroid eye disease are presented for a single centre over five years to explore the predictive factors for surgical planning. This was a retrospective study in...

Extraocular muscle disinsertion outcomes for large angle strabismus

The authors present a case series of patients who underwent surgical extraocular muscle (EOM) disinsertion for severe cranial nerve palsy or thyroid eye disease including 12 patients (13 eyes: 10 male, three female). There was one bilateral case – bilateral...

Thyroid recession drift

The authors investigated patients with thyroid ophthalmopathy (TO) who underwent unilateral inferior rectus recession for hypotropia with or without adjustable sutures to determine extent of postoperative surgical alignment. Group A comprised 13 TO patients with inferior rectus recession with adjustable...