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1048 results found

Understanding optic nerve head pericytes and glaucoma

The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...

A semi-automated algorithm for identifying glaucoma patients with blindness

Patients with sight impairment (previously referred to as partial sightedness) or severe sight impairment (previously referred to as blindness) are eligible for a certificate of visual impairment (CVI). Certification confers eligibility for a wide range of benefits administered by local...

Implantation of intraocular pressure sensor in glaucoma patients

The authors report safety and accuracy of an intraocular intraocular pressure (IOP) sensor placed in the ciliary sulcus during planned cataract surgery. Six patients underwent implantation of the device; a silicone rubber ring-shaped device encapsulating pressure sensitive capacitors and a...

RCT review of surgery for open angle glaucoma

This systematic review and meta-analysis examined eight randomised controlled trials (RCTs) to compare the intraocular pressure (IOP) reducing effect of three types of microstent implantation (Hydrus, iStent, CyPass) combined with phacoemulsification versus phacoemulsification alone for patients with open-angle glaucoma (OAG)...

Current concepts of the uveitis-glaucoma-hyphaema (UGH) syndrome

The authors discuss pathophysiology, aetiology and current management strategies of UGH syndrome. The clinical features of UGH are different than initial descriptions. UGH today is most often associated with posterior chamber IOLs that are not placed within the capsular bag...

Transcriptomic and regulatory gene associations in open angle glaucoma

The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...

Introducing Glaucoma Wise®: New ‘Beyond the Clinic’ Support for Glaucoma Patients Post Diagnosis

Time pressure means that clinicians have to focus on monitoring eye health and ‘fixing eyes’, limiting their ability to provide the emotional and practical support patients need. Glaucoma Wise is a free online resource that clinicians can direct their patients...

Comparison of structural and functional features in primary angle closure and open-angle glaucoma

In this large cross-sectional study, differences in structural and functional damage were assessed among patients with primary open-angle glaucoma (POAG) and primary angle closure glaucoma (PACG) with optical coherence tomography and reliable visual field testing. Two-hundred and eighty-three patients with...

Does vitrectomy increase the risk of glaucoma? A retrospective review from a UK hospital

The authors investigate what proportion of patients undergoing pars plana vitrectomy subsequently developed ocular hypertension or a diagnosis of glaucoma. A systematic review carried out in 2017 including seven studies found that there is evidence that pars plana vitrectomy (PPV)...

World Clinics in Ophthalmology Series: Innovations in Primary Open Angle Glaucoma

This two volume publication about current innovations in primary open angle glaucoma has persevered to come out with a comprehensive review of the latest publications in the world of glaucoma. The list of contributors includes clinicians from the field of...

Best way to detect glaucoma progression: by reflecting on the past 25 years

Glaucoma – a condition of optic neuropathy leading to progressive visual field loss often associated with raised intraocular pressure. It is fair to say that our definition for this condition has remained unchanged over the last 25 years and the...

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