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ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy

Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...

Nicotine accelerates diabetes induced retinal changes

This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...

Akimba mice, a model of human diabetic retinopathy

Diabetic retinopathy (DR) is a major complication of diabetes and a growing problem as the systemic disease becomes more prevalent. DR develops insidiously from an asymptomatic form through to vascular damage that leads to oedema and breakdown of the blood-retinal...

One-year result of XEN45 implant for glaucoma: efficacy, safety, and postoperative management

The authors report a retrospective, non-randomised interventional case series of 39 patients who underwent a standalone XEN45 implantation. All 39 patients (female: male=1.2: 1) completed 12-month follow-up. Mean age was 70.1 years (range 32–92). Primary outcome measures were the intraocular...

Surgery for lost inferior rectus muscle

This prospective study evaluated the impact of simultaneous ipsilateral superior rectus (SR) recession and superior rectus (IO) anterior transposition on the primary position alignment in six patients with traumatic loss of the inferior rectus (IR) muscle. Five males and one...

Surgery for myopic strabismus

The outcomes are reported of muscle belly union technique with medial rectus recession for cases with restriction according to the results of intraoperative forced duction testing (FDT). Surgery involved isolation of the lateral and superior recti muscles, which were separated,...

Predictive measure for alignment stability

The authors aimed to determine whether a correlation exists between the immediate operative alignment and future alignment in fixed suture strabismus surgery. This study enrolled 54 patients; seven were lost to follow-up so results are presented for 47 cases. Mean...

Surgery for superior oblique palsy with superior rectus contracture

With limited information in the literature regarding simultaneous surgery in cases with superior rectus (SR) contracture in superior oblique (SO) palsy, the authors aimed to evaluate the efficacy of combined SR/IO surgery. This was a retrospective study of 15 cases...

SO tendon advancement for SO palsy

The authors report a series of 14 patients with unilateral superior oblique (SO) palsy having unilateral SO tendon advancement with or without other vertical muscle surgery. This was a retrospective study with mean age of patients of 16.7 years and...

Four rectus muscle surgery for infantile nystagmus syndrome

The authors present a case report of infantile nystagmus syndrome (INS) with abnormal head posture (AHP) of face turn, head tilt and chin depression with a single-step surgery of all four horizontal rectus muscles. The case was a 26-year-old male...