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RTP801 as a neuroprotective and axon regenerative treatment
This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...
How a paediatric population presented with diplopia
The authors present the results of a retrospective records review of 244 children presenting with diplopia over a three-year period. The majority of cases presented to paediatric ophthalmology clinic; other routes of presentation included eye casualty, neuro-ophthalmology or another eye...Ophthalmic Imaging: From Theory to current practice
Welcome to the 14th edition of the Ophthalmic Imaging Congress. This event, focused on Imaging and all its applications in ophthalmology, will allow us to reflect on the technological advances and the progress we have made. Program: - Theoretical Sessions:...
Refractive changes over time for fully accom esotropia
The purpose of this study was to determine refractive error changes across time and to define factors contributing to decompensation in patients with fully accomodative esotropia (FAET). This was a retrospective study of 223 patients with a mean age at...In conversation with Marc Labetoulle
Following the hugely successful 10th Tear Film & Ocular Surface Society (TFOS) 2024 Conference which took place in Venice, Italy between 30 October – 2 November, we managed to have a quick Q&A with presenting attendee, Marc Labetoulle. Delivering his...
Amniotic membrane transplantation for SJS/TEN
This is a retrospective study of consecutive patients who underwent amniotic membrane transplantation (AMT) in the acute stage of Stevens-Johnson syndrome (SJS) / toxic epidermal necrolysis (TEN) from Toronto, Canada, between 2009 and 2018 and had more than three months...Visual disturbance heralding stroke: are we seeing the signs in time?
Isolated visual symptoms may be an early presenting feature of stroke, and timely recognition of such atypical cases is important because treatment for stroke has a limited time-window of efficacy. Stroke occurs in approximately 150,000 people per year in the...Demyelinating optic neuropathy
Introduction Optic neuritis (ON) is an inflammatory process affecting the optic nerve. After glaucoma, it is the most common optic neuropathy affecting patients under the age of 50. The usual presentation of typical ON is unilateral subacute loss of vision...Disseminated cutaneous zoster – a masquerade
Reactivation of varicella zoster infection in the elderly commonly presents to ophthalmologists as herpes zoster ophthalmicus (HZO), affecting the Va trigeminal dermatome. In patients with impaired immunity, zoster infection occurs with increased severity and may be complicated by visceral and...New report calls for national funding to expand life-changing eye care technology
Optometry Scotland warns of “postcode lottery” Optometry Scotland (OS), the representative body for optical professionals, has published a landmark report calling for the full integration of an early diagnostic tool in primary eyecare across Scotland. Ocular Coherence Tomography (OCT) is...Understanding and confronting bacterial endophthalmitis
Abdus Samad Ansari highlights the importance of early recognition of this condition using an unusual presentation. Endophthalmitis is a medical emergency with devastating consequences. Despite adequate treatment, severe cases frequently result in permanent blindness. Endophthalmitis involves inflammation of both the...
