You searched for "retinopathy"
Risks factors for graft preparation failure in DMEK
1 August 2016
| Magdalena Popiela
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Cornea / External Eye Disease
Diabetes mellitus (DM) makes it more difficult to prepare descemet membrane epithelial keratoplasty (DMEK) grafts due to the ‘stickiness’ of Descemet’s membrane. This retrospective study examined a classification system, where donors were scored points according to their DM related risk...
A comparison of light sources in retinal imaging
Before starting to talk about the light sources present in retinal imaging, it is necessary to start from the base: the light. Light is an electromagnetic wave whose smallest part is the photon (or quantum of light). A high frequency...Cycloplegic retinoscopy refraction versus Retinomax K-Plus 5 autorefraction
3 April 2023
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
In this study, the authors present their results comparing cycloplegic refraction with retinoscopy versus hand-held Retinomax K-Plus 5 autorefraction. The study included 213 children aged 0.1 to 20 years (426 eyes). Mean age was 6.2 ±4.4 years. They examined sphere,...
Cycloplegic autorefraction versus cycloplegic retinoscopy
5 June 2023
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
This cross-sectional study compared cycloplegic autorefraction using VISUREF 100 table top and keratometer device (Zeiss) versus cycloplegic retinoscopy. The study included 47 children (94 eyes) of which 55 eyes were excluded because of ocular disease or not aged three to...
A near miss
A 55-year-old gentleman presented with a ‘blurry patch’ to his left eye which he had noticed for the past two months. The visual acuity with correction was 6/5 in the right eye and 6/6 in the left eye on the...Diabetic Macular Oedema
1 December 2013
| Pouya Alaghband
Diabetes mellitus is a metabolic disorder that affects the metabolism of all three categories of carbohydrates, lipids and proteins. This condition is characterised by chronic hyperglycaemia [1]. This can cause end organ damage. The estimated worldwide diabetes prevalence for 2010...
Incidence, characteristics and risk factors for ROP
1 October 2016
| Jonathan Chan
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Paediatric Ophthalmology / Strabismus
This is a retrospective study performed at Seoul St Mary’s Hospital between the period of January 2009 to December 2013. The study was to determine the incidence and clinical features of, and risk factors for, retinopathy of prematurity (ROP) in...
Expert vs. non expert grading of ROP from digital video images
1 October 2015
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
The primary purpose of this study was to determine whether digital video images of the retina obtained using an indirect ophthalmoscope imaging system could be accurately graded for zone and stage of retinopathy of prematurity (ROP) and the presence of...
New mouse model of diabetes mellitus
1 April 2014
| Graham Wallace
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Retina / Uvea / Vitreous
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aldose reductase, cell signaling P-ERK1/2, P-SAPK/JNK, P-Akt, diabetic rats, diabetic retinopathy, green fluorescent proteins, growth factors VEGF, bFGF, TGF-β, retinal vascular changes, transgenic diabetic mouse models
Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...
2019 ICO-Allergan Research Fellowship awarded
4 July 2019
Dr Matias Iglicki, from the University of Buenos Aires in Argentina, has been selected as the second recipient of the International Council of Ophthalmology (ICO)-Allergan Fellowship Award, by a panel of leading experts.
100 years of insulin
3 October 2022
| Aaron Carlisle, Kieran Walshe, Lloyd Paul Aiello (Prof), Tunde Peto, Katie Curran
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Ophthalmology
*Joint first authors The centenary of the discovery of insulin is a time to celebrate one of the most significant scientific discoveries of the 20th century. Background Before 1923, Type 1 diabetes mellitus [T1DM] resulted in death from severe ketoacidosis...
Efficacy of IVC injection in the treatment of ROP
2 December 2019
| Jonathan Chan
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Retina / Uvea / Vitreous
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anti-VEGF agents, intravitreal conbercept injection, retinopathy of prematurity (ROP)
This is a retrospective consecutive case series of patients who received intravitreal conbercept (IVC) as a primary treatment from June 2015 to July 2016 for treatment of retinopathy of prematurity (ROP). Forty-eight eyes of 24 patients were included in the...