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335 results found

Safety and efficacy of a nurse-led intravitreal injection service using an Precivia® injection assist device

Nurse-led intravitreal injections have become of great importance for busy eye units. In this article, the authors present safety data from five years of a nurse-led service with the use of the Precivia® intravitreal injection assist device. Intravitreal injections of...

Results of changed treatment for retinoblastoma

Systemic chemotherapy was adopted in Kobe in 1996. In this study the authors analyse the clinical manifestations and results of treatment for patients with retinoblastoma since then. This review is of 43 eyes of 34 patients. Those with follow-up to...

Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments

Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...

Discussing treatment modalities for bilateral wet AMD

A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....

VISION 2020 LINKS: Retinoblastoma 
in Africa

The VISION 2020 LINKS Programme is part of the ‘VISION 2020: The Right to Sight’ global initiative to eliminate avoidable blindness [1]. The LINKS Programme works with overseas eye departments to help identify priorities and match their priority needs with...

Mimicked tumour seeding due to asteroid hyalosis

A case report is presented of a patient with treated retinoblastoma (RB) who later developed asteroid hyalosis which mimicked tumour seeding. The case was a 37-year-old male with presenting symptoms of vitreous floaters. A unilateral RB was diagnosed at the...

A case of ‘60-day glaucoma’

Neovascular glaucoma (NVG) has been called ‘90-’ or ‘100-day glaucoma’ in the past due to its typical development three months after the onset of central retinal vein occlusion (CRVO). In reality, NVG can occur anywhere between two weeks and two...

Risk of CNV related to angioid streaks in PXE

This retrospective cross-sectional study investigated 301 patients with pseudoxanthoma elasticum (PXE) for prevalence of choroidal neovascularisation (CNV) and macular atrophy. Some patients were excluded due to missing or poor-quality imaging or the fact that they didn’t have angioid streaks, leaving...

Characteristics of age-related distance esotropia

The primary aim of this study was to describe clinical characteristics and natural history of age-related distance esotropia (ARDET) within an adult cohort over a 20-year period. This was a retrospective review of 73 patients from 751 with adult onset...

Visual acuity outcomes after cataract surgery in type 2 diabetes (NIDDM): the action to control cardiovascular risk in diabetes (ACCORD) study

This is a retrospective case-control study of 1136 eyes enrolled in the 784 ACCORD patients receiving cataract surgery between 2001-2014. 362 / 1136 eyes had gradable fundus photography for diabetic retinopathy (DR). Seven hundred and sixty-two eyes (67.1%) achieved 20...

Statins inhibit TGFβ2 mediated fibrotic response in astrocytes

Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...

Aflibercept, bevacizumab or ranibizumab for DMO

This is a two-year randomised clinical trial of 660 patients with visual acuity impairment from diabetic macular oedema (DMO) who were randomised to monthly injections of 2.0mg aflibercept, 1.25 mg bevacizumab or 0.3mg ranibizumab. Focal or grid laser was performed...