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Ophthalmic presentations and outcomes in Erdheim-Chester disease
This is a comprehensive article describing clinical manifestations and pathogenesis of Erdheim-Chester disease (ECD) followed by a literature review of the available treatments. The authors look to compare historical treatment (HT) with vemurafenib, a BRAF inhibitor. ECD is a non-Langerhans...
Visual outcomes and predictors in optic pathway glioma
This is a retrospective study of 60 paediatric optic pathway glioma (OPG) patients (NF1 or sporadic) presenting to Great Ormond Street between 2003-2017. Median follow-up was 82 months. Analysis was divided into best and worst eye vision representing level quality...
Histopathology-guided management of ocular surface squamous neoplasia (OSSN) with corneal stromal or scleral invasion using ruthenium-106 plaque brachytherapy
This is a retrospective interventional consecutive case series of 42 eyes of 42 patients with OSSN with histopathologically proven corneal stromal and / or scleral invasion following excision biopsy. The mean tumour basal diameter was 9.3mm and thickness of 3.1mm...
Causes and outcomes of eyelid lacerations
The purpose of this study was to characterise the epidemiology of paediatric eyelid lacerations, identify risk factors for canalicular involvement and describe postoperative complications after surgical repair. This was a retrospective review of tertiary care trauma centre records in which...
Eye disorders occurring in congenital CMV
The aim of this study was to examine the relationship between congenital cytomegalovirus (CMV) infection and ophthalmological disorders that occur in children and record the frequency and type of eye disorders that occur from the infection. Of 449 potential studies,...
Surgical correction of lacrimal gland prolapse
This is a systematic review of published literature on the management of lacrimal gland prolapse or ptosis. The authors found 16 publications which contained a description of any surgical correction of a prolapsed lacrimal gland, comprising seven case reports, four...
Visual snow syndrome: a review
Visual snow syndrome (VSS) is a neurological condition characterised by visual phenomena described as dots moving across the visual field. Other visual symptoms can take the form of palinopsia, entopic phenomena, photophobia and nyctalopia. Tinnitus and migraine can be commonly...
Medium-term outcomes following photo screening
A photo-screening project of preverbal children was conducted in 2016 in Portugal consisting of enrolment of two-year-old children and referral of these if having a positive screen to paediatric ophthalmology plus a screen of four-year-old children who missed or had...
Does methanol poisoning require ophthalmic investigation?
The authors report a case series of 21 patients (41 eyes) diagnosed with acute methanol poisoning following an outbreak in Tunisia in 2020. All patients underwent a complete ophthalmological examination including visual fields, colour vision test and optical coherence tomography...
Refractive surgery for anisometropic amblyopia
The authors report the outcomes of refractive surgery with phakic intraocular lens (PIOL) implant for management of anisometropic amblyopia in children intolerant to conventional therapy. This was a retrospective study of 71 eyes of 71 patients of which 58 were...
Myopia in Han Chinese
The authors present a case-control study of 361 patients with high myopia (mean spherical equivalent of -6.0DS or lower, and axial length greater than or equal to 26mm) and 749 healthy controls (mean spherical equivalent -1.0 to +1.0DS). They tested...
