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Ophthalmologica journal cover image

VIBIM Study: One-year results of treatment of DME with aflibercept using TnE

5 October 2020 | | Retina / Uvea / Vitreous
The VIBIM study (the treat-and-extend regimen (TER) using intravitreal aflibercept in diabetic macular edema (DME) study) was designed to evaluate the efficacy of the TER using aflibercept in the management of DME for a period of two years. The authors...
Ophthalmologica journal cover image

Rebound phenomenon after IVT triamcinolone acetonide for macular oedema

7 April 2021 | | Retina / Uvea / Vitreous | Diabetic retinopathy, Macular edema, Rebound phenomenon, Retinal vein occlusion, Triamcinolone acetonide
In this retrospective study, the authors report the rebound phenomenon after intravitreal triamcinolone acetonide (IVTA) injection for macular oedema secondary to diabetic retinopathy (DR) and central (CRVO) or branch retinal vein occlusion (BRVO). The incidence of a rebound phenomenon was...

Diabetic Macular Oedema

1 December 2013 |
Diabetes mellitus is a metabolic disorder that affects the metabolism of all three categories of carbohydrates, lipids and proteins. This condition is characterised by chronic hyperglycaemia [1]. This can cause end organ damage. The estimated worldwide diabetes prevalence for 2010...

DRIL after macular oedema treatment in BRVO

1 June 2019 | | Retina / Uvea / Vitreous | Anti-vascular endothelial growth factor treatment, Branch retinal vein occlusion, Disorganization of the retinal inner layer, Spectral-domain optical coherence tomography, Visual acuity
The authors report the analysis of a single-site, retrospective, cross-sectional study to evaluate the association between disorganisation of the retinal inner layers (DRIL) and visual acuity (VA) after anti-VEGF treatment for macular oedema (MO) due to branch retinal vein occlusion...

Intravitreal dexamethasone implant for recurrent CMO secondary to IGS

1 February 2017 | | Retina / Uvea / Vitreous
In this prospective study the authors present the data obtained on the efficacy and safety of the dexamethasone implant (0.7 mg) in the treatment of recurrent cystoid macular oedema (PCME) due to Irvine–Gass syndrome in patients with uncomplicated pseudophakia (off-label...

Intravitreal bevacizumab vs. ranibizumab in the treatment of macular oedema due to BRVO

1 June 2016 | | Paediatric Ophthalmology / Strabismus | Macula, Retina
This is a randomised, prospective, non-inferiority trial of 75 patients with macular oedema due to a branch retinal vein occlusion (BRVO) who received intravitreal injections of ranibizumab or bevacizumab after 1:1 block randomisation. This study is to measure the difference...

OCT angiography and retinal vein occlusions

1 April 2016 | | Retina / Uvea / Vitreous
In this retrospective, observational case series, the authors set out to evaluate the morphology of the superficial and deep capillary plexa of eyes that suffered a retinal vein occlusion (RVO) on OCT angiography (OCTA) and compare the findings with fluorescein...

Making sense of the orthoptic assessment

1 April 2020 | | Ophthalmology, Optometry
Following the Specialty Trainee article on this topic in the February/March 2020 issue, Joe Smith provides a more detailed breakdown of the orthoptic report. Orthoptists investigate, diagnose and manage a wide variety of patients with varying problems. In this article,...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

Iris chafing from displaced single-piece acrylic IOL

4 August 2021 | | Ophthalmology, Cataract and Refractive, Imaging
A 74-year-old man had persistent 3+ cell one month following left eye cataract extraction, complicated by anterior capsular rent and zonular dialysis at 7 o’clock, with single-piece acrylic intraocular lens implantation (IOL) in the capsular bag. Figure 1: Haptic-like transillumination...

What’s new in glaucoma? Clinical trials drive practice changes, surgical advancements gather pace

1 December 2021 | | Ophthalmology, Glaucoma
Rod McNeil reviews the latest developments in the treatment of glaucoma in the UK. Primary open-angle glaucoma (POAG), which accounts for over two-thirds of all glaucoma cases, has an estimated UK prevalence in 2017 of approximately 2% of people over...

More sensitive visual acuity test for age-related macular degeneration

1 October 2016 | | Retina / Uvea / Vitreous
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...